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PAN Xiuhua, WU Zhenghong, QI Xiaole. Research status and application progress of CRISPR/Cas9 delivery system[J]. Journal of China Pharmaceutical University, 2020, 51(1): 10-18. DOI: 10.11665/j.issn.1000-5048.20200102
Citation: PAN Xiuhua, WU Zhenghong, QI Xiaole. Research status and application progress of CRISPR/Cas9 delivery system[J]. Journal of China Pharmaceutical University, 2020, 51(1): 10-18. DOI: 10.11665/j.issn.1000-5048.20200102

Research status and application progress of CRISPR/Cas9 delivery system

  • Based on the three delivery forms of CRISPR/Cas9 system at the levels of DNA, RNA and protein, this paper mainly approaches the development and new strategies of CRISPR/Cas9 delivery systems, as well as their application in the biomedical field and the clinical treatment of gene-related diseases. By summarizing and elaborating the CRISPR/Cas9 system delivery and gene therapy strategy, new ideas are provided for the discovery of innovative drugs and the development of gene therapy.
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