Citation: | CHENG Liyuan, LIU Wei, GUO Xiaoyan, GE Xiaoai, WANG Dingding, WANG Tao. Effects and mechanism of zidovudine on glucolipid metabolic balance in mice[J]. Journal of China Pharmaceutical University, 2022, 53(3): 340-347. DOI: 10.11665/j.issn.1000-5048.20220312 |
[1] |
. Lancet,2019,394:
|
[2] |
AIDS and Hepatitis C Professional Group,Society of Infectious Diseases,Chinese Medical Association. Chinese guidelines for diagnosis and treatment of HIV/AIDS (2021 edition)[J]. Chin J Intern Med(中华内科杂志),2021,60(12):1106-1128.
|
[3] |
Sapu?a M,Suchacz M,Za??ski A,et al. Impact of combined antiretroviral therapy on metabolic syndrome components in adult people living with HIV:a literature review[J]. Viruses,2022,14(1):122.
|
[4] |
Tsai FJ,Ho MW,Lai CH,et al. Evaluation of oral antiretroviral drugs in mice with metabolic and neurologic complications[J]. Front Pharmacol,2018,9:1004.
|
[5] |
Yarchoan R,Klecker RW,Weinhold KJ,et al. Administration of 3''-azido-3''-deoxythymidine,an inhibitor of HTLV-III/LAV replication,to patients with AIDS or AIDS-related complex[J]. Lancet,1986,1(8481):575-580.
|
[6] |
Clumeck N,de Wit S. Update on highly active antiretroviral therapy:progress and strategies[J]. Biomed Pharmacother,2000,54(1):7-12.
|
[7] |
Günthard HF,Saag MS,Benson CA,et al. Antiretroviral drugs for treatment and prevention of HIV infection in adults:2016 recommendations of the international antiviral society-USA panel[J]. JAMA,2016,316(2):191-210.
|
[8] |
Igoudjil A,Massart J,Begriche K,et al. High concentrations of stavudine impair fatty acid oxidation without depleting mitochondrial DNA in cultured rat hepatocytes[J]. Toxicol In Vitro,2008,22(4):887-898.
|
[9] |
Lin H,Stankov MV,Hegermann J,et al. Zidovudine-mediated autophagy inhibition enhances mitochondrial toxicity in muscle cells[J]. Antimicrob Agents Chemother,2018,63(1):e01443-e01418.
|
[10] |
Santos-Llamas A,Monte MJ,Marin JJG,et al. Dysregulation of autophagy in rat liver with mitochondrial DNA depletion induced by the nucleoside analogue zidovudine[J]. Arch Toxicol,2018,92(6):2109-2118.
|
[11] |
Ba?ó M,Morén C,Barroso S,et al. Mitochondrial toxicogenomics for antiretroviral management:HIV post-exposure prophylaxis in uninfected patients[J]. Front Genet,2020,11:497.
|
[12] |
Goodpaster BH,Sparks LM. Metabolic flexibility in health and disease[J]. Cell Metab,2017,25(5):1027-1036.
|
[13] |
Morio B,Panthu B,Bassot A,et al. Role of mitochondria in liver metabolic health and diseases[J]. Cell Calcium,2021,94:102336.
|
[14] |
Ruocco MR,Avagliano A,Granato G,et al. Metabolic flexibility in melanoma:a potential therapeutic target[J]. Semin Cancer Biol,2019,59:187-207.
|
[15] |
Smith RL,Soeters MR,Wüst RCI,et al. Metabolic flexibility as an adaptation to energy resources and requirements in health and disease[J]. Endocr Rev,2018,39(4):489-517.
|
[16] |
Lagathu C,Béréziat V,Gorwood J,et al. Metabolic complications affecting adipose tissue,lipid and glucose metabolism associated with HIV antiretroviral treatment[J]. Expert Opin Drug Saf,2019,18(9):829-840.
|
[17] |
Xiao JQ,Xu J,Shu FR,et al. Effect of Artemisia Argyi Folium ethanolic extract on blood glucose and blood lipids in diabetic mice[J]. J China Pharm Univ(中国药科大学学报),2021,52(1):71-76.
|
[18] |
Soeters MR,Soeters PB,Schooneman MG,et al. Adaptive reciprocity of lipid and glucose metabolism in human short-term starvation[J]. Am J Physiol Endocrinol Metab,2012,303(12):E1397-E1407.
|
[19] |
Gambardella J,Lombardi A,Santulli G. Metabolic flexibility of mitochondria plays a key role in balancing glucose and fatty acid metabolism in the diabetic heart[J]. Diabetes,2020,69(10):2054-2057.
|
[20] |
Tucci S,Alatibi KI,Wehbe Z. Altered metabolic flexibility in inherited metabolic diseases of mitochondrial fatty acid metabolism[J]. Int J Mol Sci,2021,22(7):3799.
|
[21] |
Toma?i? N,Kotarsky H,de Oliveira Figueiredo R,et al. Fasting reveals largely intact systemic lipid mobilization mechanisms in respiratory chain complex III deficient mice[J]. Biochim Biophys Acta Mol Basis Dis,2020,1866(1):165573.
|
[22] |
Qiu XC,Li J,Lv SH,et al. HDAC5 integrates ER stress and fasting signals to regulate hepatic fatty acid oxidation[J]. J Lipid Res,2018,59(2):330-338.
|
[23] |
Bideyan L,Nagari R,Tontonoz P. Hepatic transcriptional responses to fasting and feeding[J]. Genes Dev,2021,35(9/10):635-657.
|
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