SYNTHESIS OF 6-SUBSTITUTED-COUMARIN-3-FORMAMIDO CEPHALOSPORINS
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Graphical Abstract
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Abstract
Fifteen novel derivatives of the 6-substituted-coumarin-3-formamido cephalosporins were obtained by reacting 6-substituted coumarin-3-carboxylic acids with four cephalosporin-nuclears. Vilsmeier reagent method was mainly employed in the procedure of the c
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