Xu Jiyang, Wu Wutong, Jin Shenghao, Yao Wenbin. Chemico-Enzymatic Synthesis of Sweetener Aspartame[J]. Journal of China Pharmaceutical University, 1994, (1).
Citation:
Xu Jiyang, Wu Wutong, Jin Shenghao, Yao Wenbin. Chemico-Enzymatic Synthesis of Sweetener Aspartame[J]. Journal of China Pharmaceutical University, 1994, (1).
Xu Jiyang, Wu Wutong, Jin Shenghao, Yao Wenbin. Chemico-Enzymatic Synthesis of Sweetener Aspartame[J]. Journal of China Pharmaceutical University, 1994, (1).
Citation:
Xu Jiyang, Wu Wutong, Jin Shenghao, Yao Wenbin. Chemico-Enzymatic Synthesis of Sweetener Aspartame[J]. Journal of China Pharmaceutical University, 1994, (1).
Chemico-Enzymatic Synthesis of Sweetener Aspartame
This paper deals with the chemico-enzymatic synthesis of sweetener aspartame. N-Maleylphenylalanine methyl ester was prepared by treating maleic anhydrid with L-phenylalanine methyl ester and isomerized to N-fumarylphenylalanine methyl ester (FPM),yield 9