The Investigations into β-Cyclodextrinas HPLC Mobile Phase Chiral Additives I.The Adsorption of β-Cyclodextrin and Its Methylated Derivative on an ODS Stationary Phase
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Abstract
The adsorption characteristics of β-CD and its 2, 6-dimethyl derivative as mobile phase additives were examined by HPLC chromato graphic methods associated with a polarimetric method for quantification. Results showed that the β-CD does not adsorbe onto the ODS stationary phase but its 2, 6-dimethyl derivative produces a typical Langmuir′s isotherms of a monolayer adsorption.
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