Asymmetric Reduction of Prochiral Ketones Using Chirally Modified Sodium Borohydride

Asymmetric Reduction of Prochiral Ketones Using Chirally Modified Sodium Borohydride[J]. Journal of China Pharmaceutical University, 2000, (5): 7-9.

Citation:

Asymmetric Reduction of Prochiral Ketones Using Chirally Modified Sodium Borohydride[J]. Journal of China Pharmaceutical University, 2000, (5): 7-9.

Citation:

Asymmetric Reduction of Prochiral Ketones Using Chirally Modified Sodium Borohydride[J]. Journal of China Pharmaceutical University, 2000, (5): 7-9.

Abstract

Optical active alcohols were prepared by one-step reduction of prochiral ketones using sodium borohydride modified by \%N\%-benzyl-(\%3S,4S\%)-3,4-dihydroxy pyrrolidine.The effect of adding Lewis acids on reduction was also studied.

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