Synthesis of Terbinafine

Synthesis of Terbinafine[J]. Journal of China Pharmaceutical University, 2001, (1): 10-11.

Citation:

Synthesis of Terbinafine[J]. Journal of China Pharmaceutical University, 2001, (1): 10-11.

Citation:

Synthesis of Terbinafine[J]. Journal of China Pharmaceutical University, 2001, (1): 10-11.

Abstract

AIM: To develop a modification of the general route for the synthesis of terbinafine. METHODS: Compound (1) was synthesized from 1 bromo 6,6 dimethyl 2 hepten 4 yne(6) by reaction with N methyl 1 naphthalenemethanamine. Compound 5 was prepar

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