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Journal of China Pharmaceutical University
>
2001
>
(3)
: 8-13.
Asymmetric Synthesis of6-Fluoro-L-DOPA[J].
Journal of China Pharmaceutical University
, 2001, (3): 8-13.
Citation:
Asymmetric Synthesis of6-Fluoro-L-DOPA[J].
Journal of China Pharmaceutical University
, 2001, (3): 8-13.
Asymmetric Synthesis of6-Fluoro-L-DOPA[J].
Journal of China Pharmaceutical University
, 2001, (3): 8-13.
Citation:
Asymmetric Synthesis of6-Fluoro-L-DOPA[J].
Journal of China Pharmaceutical University
, 2001, (3): 8-13.
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(207 KB)
Asymmetric Synthesis of6-Fluoro-L-DOPA
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Abstract
AIM\ The purpose is to synthesize 6 fluoro L DOPA (FDOPA). METHODS\ The preparation of FDOPA was based on the nucleophilic displacement of fluorine for nitro group of the commercially available precursor nitroveratraldehyde, reductive iodination, a
Keywords:
6-Fluoro L DOPA
,
Chiral catalytic phase transfer alkylation
,
Synthesis
,
Enantiomeric purity
,
HPLC
,
Chiral mobile phase
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