Study on the Synthesis of Letrozole

Study on the Synthesis of Letrozole[J]. Journal of China Pharmaceutical University, 2003, (4): 85-86.

Citation:

Study on the Synthesis of Letrozole[J]. Journal of China Pharmaceutical University, 2003, (4): 85-86.

Citation:

Study on the Synthesis of Letrozole[J]. Journal of China Pharmaceutical University, 2003, (4): 85-86.

Abstract

AIM:To develop a method for preparation of letrozole . METHOD: Aniline is used as starting material to prepare letrozole by reactions of condensation, diazotization,bromination and condensation. RESULT: The structure of synthesized letrozole is confirmed

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