Studies on Synthesis and iNOS/PAF Dual Inhibitory Activity of Dithiolane Guanidine and Amidine Compounds
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Graphical Abstract
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Abstract
AIM:To search for novel potent compounds with PAF receptor antagonistic and iNOS inhibitory activities. METHOD:Guanidine and amidine functional groups were introduced into the structure of PAF receptor antagonists,and the activity of iNOS inhibitory and P
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