Synthesis of Ethyl(3R,4R,5S)-4,5-epoxy-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate

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Journal of China Pharmaceutical University > 2003 > (6): 101-102.

Synthesis of Ethyl(3R,4R,5S)-4,5-epoxy-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate[J]. Journal of China Pharmaceutical University, 2003, (6): 101-102.

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Synthesis of Ethyl(3R,4R,5S)-4,5-epoxy-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate[J]. Journal of China Pharmaceutical University, 2003, (6): 101-102.

Citation:

Synthesis of Ethyl(3R,4R,5S)-4,5-epoxy-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate[J]. Journal of China Pharmaceutical University, 2003, (6): 101-102.

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Synthesis of Ethyl(3R,4R,5S)-4,5-epoxy-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate

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AIM:Ethyl(3R,4R,5S)-4,5-epox y-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate is a key intermediate f or the preparation of novel anti-influenza drug oseltamivir and this study is to improve the chiral synthetic procedure of i t. METHOD:Title compound was
- Oseltamivir,
- Key intermediate,
- Asymmetric synthes is

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Synthesis of Ethyl(3R,4R,5S)-4,5-epoxy-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate

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