Problem analysis of residual solvents control in drug evaluation

Some problems were often found in the residual solvents control in drug evaluation，including the determination of the organic solvents for residual solvents study，the conduction of the residual solvents control of finished products，the determination of the experimental condition of headspace gas chromatography，and the establishment of the specification.These aspects were analysed with actual cases in drug evaluation process to provide some references for the pharmaceutical researchers.