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Application of internal standard correction method in the simultaneous determination of multi-components of Fructus Gardeniae[J]. Journal of China Pharmaceutical University, 2010, 41(1): 50-54.
Citation: Application of internal standard correction method in the simultaneous determination of multi-components of Fructus Gardeniae[J]. Journal of China Pharmaceutical University, 2010, 41(1): 50-54.

Application of internal standard correction method in the simultaneous determination of multi-components of Fructus Gardeniae

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  • Aim: To establish a simple and convenient quality evaluation method for Fructus Gardeniae(FG). Methods: The internal standard correction factors (fkm) of four crocetin derivatives to crocin-1 were established and the system suitability was tested.The content of crocin-1 was determined by external standard method,the contents of other crocetin derivatives were calculated by the content of crocin-1 and their fkm. Results: There was no significant difference between the test results obtained by the methods of “theoretical calculation by fkm” and “routire determination technique”. Conclusion: The internal standard correction method(the method of “theoretical calculation by fkm”) is practical and feasible in the quantitative analysis of Fructus Gardeniae.
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