• 中国精品科技期刊
  • 中国高校百佳科技期刊
  • 中国中文核心期刊
  • 中国科学引文数据库核心期刊
Advanced Search
LIU Lili, QIN Jianping, YANG Sude, WEI Yingchun, LI Xuefeng, XIAO Wei. Determination of borneol and menthol in Tongning gel by GC[J]. Journal of China Pharmaceutical University, 2014, 45(1): 76-78. DOI: 10.11665/j.issn.1000-5048.20140113
Citation: LIU Lili, QIN Jianping, YANG Sude, WEI Yingchun, LI Xuefeng, XIAO Wei. Determination of borneol and menthol in Tongning gel by GC[J]. Journal of China Pharmaceutical University, 2014, 45(1): 76-78. DOI: 10.11665/j.issn.1000-5048.20140113
shu

Determination of borneol and menthol in Tongning gel by GC

More Information
    Graphical Abstract
    • Abstract
  • To establish a GC method for the determination of borneol, isobornel and mentol in Tongning gel. The GC column was packed with 5% diphenyl and 95% dimenthyl polysiloxanc(30 m×0. 32 mm×0. 2 μm), and the split ratio and column temperature were 50 ∶1 and 88 °C, respectively. The results showed that borneol, isoborneol and menthol in Tongning gel were well-separated. The calibration curves were linear over the concentration ranger of 0. 116 9-1. 402 8mg/mL, 0. 107 8-1. 293 6mg/mL and 0. 112 7-1. 352 4 mg/mL for borneol, isoborneol and menthol, respectively. The average recoveries were 98. 02%(RSD=1. 76%), 100. 00%(RSD=1. 78%)and 101. 77%(RSD=1. 33%)respectively. The established method is accurate, sensitive and reproducible in the quality control of Tongning gel.
    • FullText(HTML)
    • References (6)
  • [1]
    Chinese Pharmacopoeia Commission.Chinese Pharmacopoeia:part 1.[M].Beijing:Chinese Medicine Science Press(中国医药科技出版社),2010:136-137,395-396.
    [2]
    Fu XH.Capillary gas chromatography simultaneous determination of menthol,methyl salicylate and synthetic borneol in Shaolin Fengshi Dieda extract[J].Chin J Pharm Anal(药物分析杂志),2011,31(6):1 111-1 115.
    [3]
    Liu X Sun F.Determination of camphor,menthol,synthetic borneol and wintergreen in Shexiang Zhuanggu plaster by GC[J].Chin Tradit Pat Med(中成药),2009,31(2):231-234.
    [4]
    Sun XM,Dai DM,Cheng XL,et al.Simultaneous determination of camphor,menthol synthetic borneol and methyl salicylate in Shexiang Zhuanggu plaster by GC method[J].Chin Tradit Pat Med(中成药),2007,29(7):1 004-1 008.
    [5]
    Zhou Z,Wei JJ.GC determination of mentholum camphora borneolum syntheticum menthyl salicylate and thymol in Wuji cream[J].Chin J Pharm Anal(药物分析杂志),2007,7(7):1 072-1 074.
    [6]
    Li MY.Determination of borneol content in Niuhuang Jiedu tablets by capillary gas chromatography[J].China Pharm(中国药业),2009,18(5):25-26.
    • Related Articles

  • Related Articles

    [1]ZHONG Shuisheng, LUO Zhu, SUN Luning, JANVIER Engelbert Agbokponto, LIANG Maozhi, DING Li. Pharmacokinetic interaction between bencycloquidium bromide nasal spray and budesonide nasal spray in healthy volunteers[J]. Journal of China Pharmaceutical University, 2013, 44(5): 447-450. DOI: 10.11665/j.issn.1000-5048.20130512
    [2]YANG Zhi-xin, WANG Jing, CHEN Zhong-xin, WANG Rui, XIE Li, CHANG Shuang. Comparative study of three pore-forming agents for colon coating solution of 5-aminosalicylic acid[J]. Journal of China Pharmaceutical University, 2012, 43(4): 325-328.
    [3]SONG Yi-ting, ZHOU Hong, SUN Wan-jin, GAO Yuan, LI Chao. Preparation and physicochemical characterization of a spray-dried lornoxicam self-microemulsifying system[J]. Journal of China Pharmaceutical University, 2012, 43(2): 137-141.
    [4]ZHAO Yan-rong, DING Li, RAO Ya-kun, TANG Xiao-wen, DING Jun-hong. Stability and degradation products of otilonium bromide in different media[J]. Journal of China Pharmaceutical University, 2010, 41(6): 548-554.
    [5]CHEN Liang, TONG Xin-yong, SHI Yuan, TAN Yan. Preparation of fluticasone propionate nasal spray and its spray characteristics[J]. Journal of China Pharmaceutical University, 2010, 41(6): 524-528.
    [6]YANG Yan, ZHU Jia-bi, ZHENG Chun-li, CHEN Sheng-jun. Preparation and characterization of aqueous polymer dispersions with high flexibility for coating[J]. Journal of China Pharmaceutical University, 2009, 40(4): 310-315.
    [7]Preparation of Compound Lonicera japonica Effervescent Spray[J]. Journal of China Pharmaceutical University, 2002, (4): 39-41.
    [8]Study onDrug Release Characteristics from Aqueous Ethylcellulose Dispersion Coated Pellets[J]. Journal of China Pharmaceutical University, 2000, (1): 27-30.
    [9]Preparation and Evaluation of Enteric Tablet Erythromycin Coated by Acrylic Resin No.2 Pseudolatex[J]. Journal of China Pharmaceutical University, 1994, (5): 267-270.
    [10]Studies on Aqueous Coating Technique for Acetylsalicylic Acid Enteric Tablets[J]. Journal of China Pharmaceutical University, 1991, (3): 154-157.

  • Cited by

    Periodical cited type(5)

    1. 阿文丽，张衡頔，胡吉蕾，肖春秀，凡蝶，康超，时皎皎，林宁. 姜黄素在低压低氧环境下对机体保护作用机制的研究进展. 中国医药导报. 2024(06): 50-53 .
    2. 郑光艳，吴文丽，刘泽梅，车鑫，王立红. 微流控技术制备槲皮素纳米晶及其大鼠体内药动学研究. 中国医药工业杂志. 2024(04): 519-526 .
    3. 陈榕，颜烨，何梓炫，黄小红，林昭妍. 提升姜黄素疗效的策略及技术研究进展. 中草药. 2024(15): 5315-5330 .
    4. 李双霞，薛晶晶. 浅谈浸出制剂的技术难点与研发策略. 基层中医药. 2023(02): 70-74 .
    5. 王培，牛丽丽，李静宇，耿红梅. 医用多孔支架材料的制备及缓释性能分析. 中国塑料. 2022(11): 73-78 .

    Other cited types(3)

Catalog

    Get Citation
    PDF
    XML
    Article views (1383) PDF downloads (2107) Cited by(8)
    Turn off MathJax
    Article Contents
    Abstract
    References
    Related Articles

    Copyright © Journal of China Pharmaceutical University苏ICP备12050101号-2

    Address：24 Tongjia Lane, Nanjing City, Jiangsu Province （210009）Tel: 025-83271566E-mail: xuebao@cpu.edu.cn

    Supported by: Beijing Renhe Information Technology Co., Ltd.  Baidu Analytics

    Total visits：311885

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return