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Opportunities and challenges of small-molecule modulation of protein-protein interactions
CHEN Zicong, YOU Qidong, WANG Lei
2026, 57(5): 551-562. DOI: 10.11665/j.issn.1000-5048.2026062405
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Kinase molecular glues: a new strategy for inducing proximity to regulate protein-protein interactions
ZHAO Can, WANG Chaofan, LU Xiaoyun
2026, 57(5): 563-574. DOI: 10.11665/j.issn.1000-5048.2026051403
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Research progress on the structural basis and biased signaling of fibroblast growth factor-receptor protein interactions
QI Jie, LI Yufeng, TIAN Shuliang, SONG Lintao, HUANG Zhifeng
2026, 57(5): 575-584. DOI: 10.11665/j.issn.1000-5048.2026073001
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Advances in the roles and mechanisms of the histone deacetylase 9 interaction network in cardiovascular diseases
WEI Taofeng, DAI Haibin
2026, 57(5): 585-596. DOI: 10.11665/j.issn.1000-5048.2026042706
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Design, synthesis and biological evaluation of focal adhesion kinase degraders based on a rapid assembly strategy
HOU Liyuan, HUANG Wenhai, CHE Jinxin, WU Mingfei
2026, 57(5): 597-606. DOI: 10.11665/j.issn.1000-5048.2026072103
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Chemical synthesis of trisaccharide intermediates related to Streptococcus pneumoniae serotype 9N capsular polysaccharide
CHEN Ziyue, QIN Chunjun, FU Junjie, TIAN Guangzong, ZOU Xiaopeng, HU Jing, YIN Jian
2026, 57(5): 607-614. DOI: 10.11665/j.issn.1000-5048.2026021301
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Construction and evaluation of siTNF-α delivery system based on sulfated hyaluronan-polyethyleneimine-polyphenol conjugates
LI Ruiting, SONG Ying, HAN Ziyan, DING Fangfang, BU Linghan, YAN Yishu
2026, 57(5): 615-626. DOI: 10.11665/j.issn.1000-5048.2025121601
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Phycocyanin-tannic acid nanoparticle-loaded inulin gel for the treatment of ulcerative colitis in mice
YE Jialong, ZHENG Yunhe, ZHANG Yue, WANG Ting, ZHANG Chen, WANG Ke
2026, 57(5): 627-635. DOI: 10.11665/j.issn.1000-5048.2026030501
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Preparation of cytomimetic microspheres and their application in cancer metastasis therapy
HUANG Ziyi, ZHU Yanan, XUE Luxin, LIANG Huan, SUN Minjie, ZHOU Zhanwei
2026, 57(5): 636-648. DOI: 10.11665/j.issn.1000-5048.2025110504
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Construction and evaluation of an oral colon-targeting nano-delivery system for low molecular weight heparin
HONG Shujia, YAN Yan
2026, 57(5): 649-658. DOI: 10.11665/j.issn.1000-5048.2026031603
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Determination of levomethorphan, dextromethorphan and dextrorphan in hair and urine by LC-MS/MS
ZHANG Kejun, MIAO Xingang, CAI Yuyan, LU Limei, CHEN Qihua, KE Zunhe
2026, 57(5): 659-665. DOI: 10.11665/j.issn.1000-5048.2026031001
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Establishment and validation of an analytical method for related substances in namodenoson, an investigational new drug for hepatocellular carcinoma
CAI Liangliang, WU Wenyi, QIN Jisu, TANG Zhiyuan
2026, 57(5): 666-671. DOI: 10.11665/j.issn.1000-5048.2026041002
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Mechanism of AEG-1 reducing cisplatin sensitivity of gastric cancer cells by upregulating eIF4E expression
SUN Jiajie, QIAN Xixi, BAI Zhihui, WANG Xuerong, HUANG Wenbin
2026, 57(5): 672-682. DOI: 10.11665/j.issn.1000-5048.2026040801
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Liquid-liquid phase separation in disease: mechanisms of formation and regulation
LIU Haotian, GUO Minshan, CAI Ting
2026, 57(5): 683-691. DOI: 10.11665/j.issn.1000-5048.2026022602
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Advances in research on eukaryotic elongation factor 2 as a potential target for rapid-acting antidepressants
FAN Hairan, WANG Rong, WANG Hao, HU Xiaolong
2026, 57(5): 692-700. DOI: 10.11665/j.issn.1000-5048.2026031604
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Research progress on N6-methyladenosine regulation of hippocampal neurogenesis in the treatment of ischemic stroke
FAN Wenxiang, LI Ji, FAN Wenqiang, XU Chi
2026, 57(5): 701-710. DOI: 10.11665/j.issn.1000-5048.2026033002
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