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ZHANG Wenxin, ZHANG Chunxia, HAN Lingfei, et al. Progress on the value of multi-target effect of Gouteng based on network pharmacology study[J]. J China Pharm Univ, 2025, 56(3): 376 − 381. DOI: 10.11665/j.issn.1000-5048.2024070502
Citation: ZHANG Wenxin, ZHANG Chunxia, HAN Lingfei, et al. Progress on the value of multi-target effect of Gouteng based on network pharmacology study[J]. J China Pharm Univ, 2025, 56(3): 376 − 381. DOI: 10.11665/j.issn.1000-5048.2024070502

Progress on the value of multi-target effect of Gouteng based on network pharmacology study

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This study was supported by the National Natural Science Foundation of China (No.81973207)

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  • Received Date: July 04, 2024
  • Revised Date: August 26, 2024
  • Accepted Date: September 23, 2024
  • Uncaria rhynchophylla (Miq.)Miq. ex Havil (Gouteng) is a dry and hooked stem branch of Rubiaceae, which contains chemical components including alkaloids, terpenoids, flavonoids and organic acids. It has antioxidant, anti-inflammatory, and potential therapeutic effects on various diseases. The characteristics of network pharmacology are multi-component, multi-target and multi-channel, which can analyze the complex mechanism of the active ingredient group of traditional Chinese medicine and the disease markers, and clarify the relationship between drugs, targets and diseases. This review summarises the research progress of the intervention of Gouteng in neurological disorders, cardiovascular diseases, inflammation, and other diseases based on network pharmacology and provides a theoretical foundation for the clinical application of Gouteng.

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