Citation: | WU Yuzheng, WANG Guangji, HAO Haiping. Advances of metabolomic research of traditional Chinese medicine[J]. Journal of China Pharmaceutical University, 2014, 45(2): 129-135. DOI: 10.11665/j.issn.1000-5048.20140201 |
[1] |
Lao YM,Jiang JG,Yan L.Application of metabonomic analytical techniques in the modernization and toxicology research of traditional Chinese medicine[J].Br J Pharmacol,2009,157(7):1 128-1 141.
|
[2] |
Nicholson JK,Lindon JC.Systems biology: metabonomics[J].Nature,2008,455(7 216):1 054-1 056.
|
[3] |
Gates SC,Sweeley CC.Quantitative metabolic profiling based on gas chromatography[J].Clin Chem,1978,24(10):1 663-1 673.
|
[4] |
Lindon JC,Holmes E,Nicholson JK.So what′s the deal with metabonomics[J] ? Anal Chem,2003,75(17):384A-391A.
|
[5] |
Zou HY,Chen ZJ,Zheng JM.The application of GC-MS in the study of traditional Chinese medicine[J].Modern Business Trade Industry(现代商贸工业),2010(9):362-364.
|
[6] |
Wu L,Hao H,Wang G.LC/MS based tools and strategies on qualitative and quantitative analysis of herbal components in complex matrixes[J].Curr Drug Metab,2012,13(9):1 251-1 265.
|
[7] |
Seger C,Sturm S,Stuppner H.Mass spectrometry and NMR spectroscopy: modern high-end detectors for high resolution separation techniques-state of the art in natural product HPLC-MS,HPLC-NMR,and CE-MS hyphenations[J].Nat Prod Rep,2013,30(7):970-987.
|
[8] |
Madler S,Boeri EE,Zenobi R.MALDI-ToF mass spectrometry for studying noncovalent complexes of biomolecules[J].Top Curr Chem,2013,331:1-36.
|
[9] |
Fan TW,Lorkiewicz PK,Sellers K,et al.Stable isotope-resolved metabolomics and applications for drug development[J].Pharmacol Ther,2012,133(3):366-391.
|
[10] |
Goodacre R.Making sense of the metabolome using evolutionary computation: seeing the wood with the trees[J].J Exp Bot,2005,56(410):245-254.
|
[11] |
Ren HC,Wang GJ,A JY,et al.The advancement of metabolomics analytical techniques and data statistics[J].J Clin Pharmacol Ther(中国临床药理学与治疗学),2007,12(12):1 332-1 338.
|
[12] |
Zheng CN.Homologue family based strategy for metabolism and pharmacokinetic research of herb medicine: metabolic rules research of ginsenosides in Sheng-mai compound prescription(以同系成分群为结构单元的中药药代动力学:生脉方中人参总皂苷代谢处置规律研究)[D].Nanjing:China Pharmaceutical University,2006.
|
[13] |
Cui N.In vitro and in vivo herblome strategy based complicated components metabolism and pharmacodynamic materials research of Mai-Luo-Ning injection(基于体内外物质组策略的脉络宁注射液复杂成分代谢与药效物质研究)[D].Nanjing:China Pharmaceutical University,2006.
|
[14] |
Hao H,Cui N,Wang G,et al.Global detection and identification of nontarget components from herbal preparations by liquid chromatography hybrid ion trap time-of-flight mass spectrometry and a strategy[J].Anal Chem,2008,80(21):8 187-8 194.
|
[15] |
Xie T,Liang Y,Hao H,et al.Rapid identification of ophiopogonins and ophiopogonones in Ophiopogon japonicus extract with a practical technique of mass defect filtering based on high resolution mass spectrometry[J].J Chromatogr A,2012,1 227:234-244.
|
[16] |
Yin H,Li SG,Bai XF.The research method and application of botanic metabolomics[J].Chin Bull Bot(植物学报),2005,22(5):532-540.
|
[17] |
Yang FQ,Li SP,Chen Y.The fingerprint of Ezhu by GC-MS[J].Acta Pharm Sin(药学学报),2005,40(11):1 013-1 018.
|
[18] |
Yao X,Zhou G,Tang Y,et al.UPLC-PDA-TOF/MS coupled with multivariate statistical analysis to rapidly analyzeand evaluate Ginkgo biloba leaves from different origin.LID - 10.1002/dta.DOI 10.1002/dta.1477.
|
[19] |
Kim N,Kim K,Choi BY,et al.Metabolomic approach for age discrimination of Panax ginseng using UPLC-Q-TOF MS[J].J Agric Food Chem,2011,59(19):10 435-10 441.
|
[20] |
Wang XJ,Li ZY,Xue SY,et al.Quality control over different processed products of Polygalae radix[J].Chin Tradit Herb Drugs(中草药),2012,43(9):1 727-1 737.
|
[21] |
He SM,Chan E,Zhou SF.ADME properties of herbal medicines in humans: evidence,challenges and strategies[J].Curr Pharm Des,2011,17(4):357-407.
|
[22] |
Wang CZ,Kim KE,Du GJ,et al.Ultra-performance liquid chromatography and time-of-flight mass spectrometry analysis of ginsenoside metabolites in human plasma[J].Am J Chin Med,2011,39(6):1 161-1 171.
|
[23] |
Wan JY,Liu P,Wang HY,et al.Biotransformation and metabolic profile of American ginseng saponins with human intestinal microflora by liquid chromatography quadrupole time-of-flight mass spectrometry[J].J Chromatogr A,2013,1 286:83-92.
|
[24] |
Gong P,Cui N,Wu L,et al.Chemicalome and metabolome matching approach to elucidating biological metabolic networks of complex mixtures[J].Anal Chem873(2):151-158.
|
[25] |
Yue R,Zhao L,Hu Y,et al.Rapid-resolution liquid chromatography TOF-MS for urine metabolomic analysis ofcollagen-induced arthritis in rats and its applica乴噩奯煮荳牛J].J Ethnopharmacol,2013,145(2):465-475.
|
[26] |
Liu X,Zhu W,Guan S,et al.Metabolomic ?nalysis of anti-hypoxia and anti-anxi?ty ef?ects of Fu Fang Jin Jing oral liquid[J].PLoS ONE,2013,8(10):e78281.
|
[27] |
礠嬠Z畨呯祮孧 艆攬牌iu X,Zhou Q,et al.1H NMR spectroscopy analysis of metabolites in the kidneys provides new insight into pathophysiological mechanisms: applications for treatment with Cordycepssinensis[J].,2012,27(2):556-565.
|
[28] |
Qiao X,Ye M,Xiang C,et al.Metabolic regulatory effects of licorice: a bile acid metabonomic study by liquid chromatography coupled with tandem mass spectrometry[J].Steroids,2012,77(7):745-755.
|
[29] |
Jiang H,Nie L,Li Y,et al.Application of ultra-performance liquid chromatography coupled with massspectrometry to metabonomic study on spontaneously hypertensive rats andintervention effects of Ping Gan prescription[J].J Sep Sci,2012,35(4):483-489.l formula intervention: an exploratory metabonomics study of blood plasma and urine[J].Mol Biosyst,2013,9(1):77-87.
|
[30] |
Wang Y,Ma L,Sun Y,et al.Metabonomics study on the hot syndrome of traditional Chinese medicine by rapid resolution liquid chromatography combined with quadrupole time-of-flight tandemmass spectrometry[J].Arch Pharm Res,2013.DOI: 10.1007/s12272-013-0250-z.
|
[31] |
Wang J,Yuan Z,Kong H,et al.Exploring the mechanism of rhizoma coptidis in treating type II diabetesmellitus based on metabolomics by gas chromatography-mass spectrometry[J].Se Pu,2012,30(1):8-13.
|
[32] |
Song X,Wang J,Wang P,et al.(1)H NMR-based metabolomics approach to evaluate the effect of Xue-Fu-Zhu-Yu decoction on hyperlipidemia rats induced by high-fat diet[J].J Pharm Biomed Anal,2013,78-79:202-210.
|
[33] |
Liu X,Zhang S,Lu X,et al.Metabonomic study on the anti-osteoporosis effect of Rhizoma Drynariae and itsaction mechanism using ultra-performance liquid chromatography-tandem massspectrometry[J].J Ethnopharmacol,2012,139(1):311-317.
|
[34] |
Xiang L,Jiang P,Zhan C,et al.The serum metabolomic study of intervention effects of the traditional Chinese medicine Shexiang Baoxin Pill and a multi-component medicine polypill in thetreatment of myocardial infarction in rats[J].Mol Biosyst,2012,8(9):2 434-2 442.
|
[35] |
Jiang P,Dai W,Yan S,et al.Biomarkers in the early period of acute myocardial infarction in rat serum andprotective effects of Shexiang Baoxin Pill using a metabolomic method[J].J Ethnopharmacol,2011,138(2):530-536.
|
[36] |
Jiang P,Dai W,Yan S,et al.Potential biomarkers in the urine of myocardial infarction rats: a metabolomic method and its application[J].Mol Biosyst,2011,7(3):824-831.
|
[37] |
Tan G,Liao W,Dong X,et al.Metabonomic profiles delineate the effect of traditional Chinese medicine sinidecoction on myocardial infarction in rats[J].PLoS ONE,2012,7(4):e34157.
|
[38] |
Tan G,Lou Z,Liao W,et al.Potential biomarkers in mouse myocardium of doxorubicin-induced cardiomyopathy:a metabonomic method and its application[J].PLoS ONE,2011,6(11):e27683.
|
[39] |
Tan G, Lou Z, Liao W, et al. Hydrophilic interaction and reversed-phase ultraperformance liquid chromatography TOF-MS for serum metabonomic analysis of myocardial infarction in rats and its applications[J].Mol Biosyst,2012,8(2):548-556.
|
[40] |
Zhao X,Zhang Y,Meng X,et al.Effect of a traditional Chinese medicine preparation Xindi soft capsule on ratmodel of acute blood stasis: a urinary metabonomics study based on liquid chromatography-mass spectrometry[J].J Chromatogr B Analyt Technol Biomed Life Sci
|
[1] | ZHU Song, JIANG Jing, LIU Yang, ZOU Wenyu, HU Pengwei, LU Yuting, SONG Min, HANG Taijun. Structural identification of the related substances of lorazepam tablets by LC-MS[J]. Journal of China Pharmaceutical University, 2021, 52(5): 555-565. DOI: 10.11665/j.issn.1000-5048.20210507 |
[2] | LIANG Fangmei, NI Yueling, WANG Lu, HANG Taijun, SONG Min. Structural identification of the related substances of fusidic acid by LC-MS[J]. Journal of China Pharmaceutical University, 2018, 49(3): 322-332. DOI: 10.11665/j.issn.1000-5048.20180311 |
[3] | YIN Xiaoya, WANG Cheng, MING Guojun, HANG Taijun. Identification of the related substances in pioglitazone hydrochloride by hyphenated LC-MS techniques[J]. Journal of China Pharmaceutical University, 2017, 48(6): 701-710. DOI: 10.11665/j.issn.1000-5048.20170611 |
[4] | XU Yunhui, JIANG Xueyang, XU Jian, JIANG Renwang, ZHANG Jie, XIE Zijian, FENG Feng. Chemical constituents from Callicarpa kwangtungensis Chun[J]. Journal of China Pharmaceutical University, 2016, 47(3): 299-302. DOI: 10.11665/j.issn.1000-5048.20160309 |
[5] | CHEN Wenhua, ZOU Limin, ZHANG Fei, ZHANG Liandi, LIAO Mingyi, DING Li. Identification of the related substances in bendamustine hydrochloride[J]. Journal of China Pharmaceutical University, 2015, 46(3): 333-338. DOI: 10.11665/j.issn.1000-5048.20150312 |
[6] | MA Lin, ZHANG Rongfei, YU Shule, WU Zhengfeng, ZHAO Shouxun, Wang Lei, YE Wencai, ZHANG Jian, YIN Zhiqi. Chemical constituents of Fructus Gleditsiae Abnormalis[J]. Journal of China Pharmaceutical University, 2015, 46(2): 188-193. DOI: 10.11665/j.issn.1000-5048.20150209 |
[7] | CHANG Bo, XIAO Linjing, ZHANG Jian, ZHAO Shouxun, YE Wencai, YIN Zhiqi. Chemical constituents from Abies ernestii var.salouenensis[J]. Journal of China Pharmaceutical University, 2014, 45(1): 43-47. DOI: 10.11665/j.issn.1000-5048.20140107 |
[8] | RAO Ya-kun, DING Li, YU Yong. Structural identification of two major impurities in sodium levofolinate[J]. Journal of China Pharmaceutical University, 2012, 43(4): 350-354. |
[9] | Chemical constituents from Senecio nemorensis.[J]. Journal of China Pharmaceutical University, 2010, 41(1): 26-28. |
[10] | WANG Ying, YIN Hong-ping, CHEN Tao, WANG Min. Preliminary structural identification and protection on renal cell injury of acidic polysaccharide from Cordyceps sinensis[J]. Journal of China Pharmaceutical University, 2009, 40(6): 559-564. |