• 中国精品科技期刊
  • 中国高校百佳科技期刊
  • 中国中文核心期刊
  • 中国科学引文数据库核心期刊
Advanced Search
ZHUANG Tao, XU Baolei, HUANG Liru, CHEN Xingyi, LIANG Jingyu, QU Wei. A new norlignan from Saururus chinensis[J]. Journal of China Pharmaceutical University, 2014, 45(4): 410-412. DOI: 10.11665/j.issn.1000-5048.20140405
Citation: ZHUANG Tao, XU Baolei, HUANG Liru, CHEN Xingyi, LIANG Jingyu, QU Wei. A new norlignan from Saururus chinensis[J]. Journal of China Pharmaceutical University, 2014, 45(4): 410-412. DOI: 10.11665/j.issn.1000-5048.20140405
shu

A new norlignan from Saururus chinensis

More Information
    Graphical Abstract
    • Abstract
  • A new norlignan, named sauchinolide A( 1 ), together with two known tetrahydrofuran lignans( 2 and 3 ), were isolated from the 95% EtOH extract of the whole plants of Saururus chinensis. All of them were isolated from the family Saururaceae for the first time. The effect of the obtained compounds on hypoxia/reoxygenation(H/R)injury in human endothelial EA. hy926 cells were preliminarily evaluated. The results showed that compound 2 exhibited moderate protective effect against H/R injury in EA. hy926.
    • FullText(HTML)
    • References (11)
  • [1]
    Sung SH,Kim YC.Hepatoprotective diastereomeric lignans from Saururus chinensis herbs[J].J Nat Prod,2000,63(7):1 019-1 021.
    [2]
    Seo CS,Zheng MS,Woo MH,et al.Lignans from the roots of Saururus chinensis[J].J Nat Prod,2008,71(10):1 771-1 774.
    [3]
    Kang TH,Cho H,Oh H,et al.Flavonol glycosides with free radical-scavenging activity of Saururus chinensis[J].Fitoterapia,2005,76(1):115-117.
    [4]
    Lee YJ,Kim J,Yi JM,et al.Anti-proliferative neolignans from Saururus chinensis against human cancer cell lines[J].Biol Pharm Bull,2012,35(8):1 361-1 366.
    [5]
    Qu W,Liang JY.Two isomeric compounds of C13-norisoprenoids from Saururus chinensis(Lour.)Baill[J].Chin Chem Lett,2009,20(11):1 342-1 344.
    [6]
    Lee YK,Seo CS,Lee CS,et al.Inhibition of DNA topoisomerases I and II and cytotoxicity by lignans from Saururus chinensis[J].Arch Pharm Res,2009,32(10):1 409-1 415.
    [7]
    Lee J,Huh MS,Kim YC,et al.Lignan,sesquilignans and dilignans,novel HIV-1 protease and cytopathic effect inhibitors purified from the rhizomes of Saururus chinensis[J].Antiviral Res,2010,85(2):425-428.
    [8]
    Lee AK,Sung SH,Kim YC,et al.Inhibition of lipopolysaccharide-inducible nitric oxide synthase,TNF-α and COX-2 expression by sauchinone effects on I-κBα phosphorylation,C/EBP and AP-1 activation[J].Brit J Pharmacol,2003,139(1):11-20.
    [9]
    Conserva LM,Silva MS,Brazfilho R.Lignans from Aristolochia Birostris[J].Phytochemistry,1990,29(1):257-260.
    [10]
    Toferna B,Jenett-Siems K,Siems K,et al.Bonaspectins and neobonaspectins,frirst sesquilignans and sesquineolignans from a convolvulaceous species[J].Phytochemistry,2000,53(1):119-128.
    [11]
    Jahn U,Rudakov D.Tetrahydrofuran lignans via tandem oxidative anionic-radical processes or reductive radical cyclizations[J].Org Lett,2006,8(20):4 481-4 484.
    • Related Articles

  • Cited by

    Periodical cited type(3)

    1. 胡彤，李爽，钟卫鸿. 基于酸信号转导系统的细菌耐酸机制及其应用. 生物工程学报. 2024(03): 644-664 .
    2. 吴晓妍，吴剑梅，傅丹丹，涂健，宋祥军，邵颖，祁克宗. hipA对禽致病性大肠杆菌生物学特性和致病性的影响. 西北农林科技大学学报(自然科学版). 2023(08): 11-18+28 .
    3. 郝雪雁，刘梦晓，韩紫依，房立霞，曹英秀. 大肠杆菌的耐酸机制及其改造研究进展. 微生物学通报. 2023(10): 4667-4680 .

    Other cited types(1)

Catalog

    Get Citation
    PDF
    XML
    Article views (1317) PDF downloads (1597) Cited by(4)
    Turn off MathJax
    Article Contents
    Abstract
    References

    Copyright © Journal of China Pharmaceutical University苏ICP备12050101号-2

    Address：24 Tongjia Lane, Nanjing City, Jiangsu Province （210009）Tel: 025-83271566E-mail: xuebao@cpu.edu.cn

    Supported by: Beijing Renhe Information Technology Co., Ltd.  Baidu Analytics

    Total visits：304017

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return