Citation: | WEN Liujing, WANG Chen. Application and research progress of pharmaco-metabonomics in the diagnosis and treatment of tumor[J]. Journal of China Pharmaceutical University, 2015, 46(4): 400-405. DOI: 10.11665/j.issn.1000-5048.20150403 |
[1] |
Huang Y,Xu FG,Zhang W,et al. Progress for pharmacometabolomics and its applications[J].J China Pharm Univ(中国药科大学学报),2013,44(2):105-112.
|
[2] |
German JB,Bauman DE,Burrin DG,et al.Metabolomics in the opening decade of the 21st century:building the roade to individualized health[J].J Nute,2004,134(12):2729-2732.
|
[3] |
Nicholson JK,Wilson ID.Opinion:understanding ‘global’ systems biology:metabonomics and the continuum of metabolism[J].Nat Rev Drug Discov,2003,2(8):668-676.
|
[4] |
Nicholson JK,Lindon JC,Holmes E.Metabonomics:understanding the metabolic response of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data[J].Xenobiotica,1999,29(11):1181-1189.
|
[5] |
Fiehn O,Kopka J,Dormann P,et al.Metabolite profiling for plant functional genomics[J].Nat Biotechnol,2000,18(11):42-43.
|
[6] |
Clayton TA,Lindon JC,Cloarec O,et al.Pharmaco-metabonomic phenotyping and personalized drug treatment[J].Nature,2006,440(7087):1073-1077.
|
[7] |
Bugrim A,Nikolskaya T,Nikolsky Y.Early prediction of drug metabolism and toxicity:systems biology approach and modeling[J].Drug Discov Today,2004,9(3):127-135.
|
[8] |
Jaki BU,Franzblau SG,Cho SH,et al.Development of an extraction method for mycobacterial metabolome analysis[J].J Pharm Biomed Anal,2006,41(1):196-200.
|
[9] |
Schaub J,Schiesling C,Reuss M,et al.Integrated sampling procedure for metabolome analysis[J].Biotechnol Prog,2006,22(5):1434-1442.
|
[10] |
Bruce SJ,Tavazzi I,Parisod V,et al.Investigation of human blood plasma sample preparation for performing metabolomics using ultrahigh performance liquid chromatography/mass spectrometry[J].Anal Chem,2009,81(9):3285-3296.
|
[11] |
Rmisch-Margl W,Prehn C,Bogumil R,et al.Procedure for tissue sample preparation and metabolite extraction for high-throughput targeted metabolomics[J].Metabolomics,2011,8(1):133-142.
|
[12] |
Korfmacher WA.Foundation review:principles and applications of LC-MS in new drug discovery[J].Drug Discov Today,2005,10(20):1357-1367.
|
[13] |
Gao H,Materne OL,Howe DL,et al.Method for rapid metabolite profiling of drug candidates in fresh hepatocytes using liquid chromatography coupled with a hybrid quadrupole linear ion trap[J].Rapid Commun Mass Spectrom,2007,21(22):3683-3693.
|
[14] |
Tiller PR,Yu S,Castro-Perez J,et al.High-throughput,accurate mass liquid chromatography/tandem mass spectrometry on a quadrupole time-of-flight system as a ‘first-line’ approach for metabolite identification studies[J].Rapid Commun Mass Spectrom,2008,22(7):1053-1061.
|
[15] |
Tulpan D,Leger S,Belliveau L,et al.MetaboHunter:an automatic approach for identification of metabolites from 1H-NMR spectra of complex mixtures [J].BMC Bioinformatics,2011.doi: 10.1186/1471-2105/12/400.
|
[16] |
Wishart DS,Jewison T,Guo AC,et al.HMDB 3.0—the human metabolome database in 2013[J].Nucleic Acids Res,2012.doi: 10.1093/nar/gks1065.
|
[17] |
Feng B,Zheng MH,Zheng YF,et al.Normal and modified urinary nucleosides represent novel biomarkers for colorectal cancer diagnosis and surgery monitoring[J].J Gastroenterol Hepatol,2005,20(12):1913-1919.
|
[18] |
Ma Y,Liu W,Peng J,et al.A pilot study of gas chromatograph/mass spectrometry-based serum metabolic profiling of colorectal cancer after operation[J].Mol Biol Rep,2010,37(3):1403-1411.
|
[19] |
Wibom C,Surwiec I,Mörén L,et al.Metabolomic patterns in glioblastoma and changes during radiotherapy:a clinical microdialysis study[J].J Proteome Res,2010,9(6):2909-2919.
|
[20] |
Kim KB,Yang JY,Kwack SJ,et al.Potential metabolomic biomarkers for evaluation of adriamycin efficacy using a urinary 1H-NMR spectroscopy[J].J Appl Toxicol,2012,33(11):1251-1259.
|
[21] |
Pan X,Wilson M,Mirbahai L,et al.In vitro metabonomic study detects increases in UDP-GlcNAc and UDP-GalNAc,as early phase markers of cisplatin treatment response in brain tumor cells[J].J Proteome Res,2011,10(8):3493-3500.
|
[22] |
Nakayama Y,Matsumoto K,Inoue Y,et al.Correlation between the urinary dihydrouracil-uracil raito and the 5-Fu plasma concentration in patients treated with oral 5-FU analogs[J].Anticancer Res,2010,26(5):3983-3988.
|
[23] |
Backshall A,Sharma R,Clarke SJ,et al.Pharmacometabonomic profiling as a predictor of toxicity in patients with inoperable colorectal cancer treated with capecitabine[J].Clin Cancer Res,2011,17(9):3019-3028.
|
[24] |
Fan TWM,Lane AN.Structure-based profiling of metabolites and isotopomers by NMR[J].Prog Nucl Magn Reson Spectrosc,2008,52(2/3):69-117.
|
[25] |
Paleari L,Trombino S,Falugi C.Marine sponge-derived polymeric alkylpyridinium salts as a novel tumor chemotherapeutic targeting the cholinergic system in lung tumors[J].Int J Oncolm,2006,29(6):1381-1388.
|
[26] |
Tian YP,He JM,Zhang RP,et al.Integrated rapid resolution liquid chromatography-tandem mass spectrometric approach for screening and identification of metabolites of the potential anticancer agent 3,6,7-trimethoxyphenanthroindolizidine in rat urine[J].Anal Chim Acta,2012,731(20):60-67.
|
[27] |
Lutz NW,Franks SE,Frank MH,et al.Investigation of multidrug resistance in cultured human renal cell carcinoma cells by 31P-NMR spectroscopy and treatment survival assays[J].MAGMA,2005,18(3):144-161.
|
[28] |
Kominsky DJ,Klawitter J,Brown JL,et al.Abnormalities in glucose up-take and metabolism in imatinib-resistant human BCR-ABL-positive cells[J].Clin Cancer Res,2009,15(10):3442-3450.
|
[29] |
El-Deredy W.Pattern recognition approaches in biomedical and clinical magnetic resonance spectroscopy:a review[J].NMR Biomed,1997,10(3):99-124.
|
[30] |
Wang X,Yan SK,Dai WX,et al.A metabonomic approach to chemosensitivity prediction of cisplatin plus 5-fluorouracil in a human xenograft model of gastric cancer[J].Int J Cancer,2010,127(12):2841-2850.
|
[31] |
Huuse EM, Jensen LR, Goa PE, et al. Monitoring the effect of docetaxel treatment in MCF7 xenografts using multimodal in vivo and ex vivo magnetic resonance methods,histopathology,and gene expression[J].Trans Oncol,2010,3(4):252-263.
|
[32] |
Cavill R,Kamburov A,Ellis JK,et al.Consensus-phenotype integration of transcriptomic and metabolomic data implies a role for metabolism in the chemosensitivity of tumour cells[J].PLoS Comput Biol,2011,7(3):e1001113.
|
[33] |
Zha W,Jiye A,Qian S,et al.Chronic myeloid leukemia patients sensitive and resistant to imatinib treatment show different metabolic responses[J].PLoS One,2010,5(10):e13186.
|
[34] |
Thysell E,Surowiec I,Hörnberg E,et al.Metabolomic characterization of human prostate cancer bone metastases reveals increased levels of cholesterol[J].PLoS One,2010,5(12):e14175.
|
[35] |
Neckers L.Using natural product inhibitors to validate Hsp90 as a molecular target in cancer[J].Curr Top Med Chem,2006,6(11):1163-1171.
|
[36] |
Shen GQ.Study of animal tumor model based metabolomics and pharmaco-metabolomic approach using LC-MS/MS[D/OL].Beijing:Chinese Academy of Medical Sciences & Peking Union Medical College,2011.http://cdmd.cnki.com.cn/Article/CDMD-10023-1011163897.htm.
|
[37] |
Kalluri U,Naiker M,Myers MA.Cell culture metabolomics in the diagnosis of lung cancer—the influence of cell culture conditions[J].J Breath Res,2014.doi: 10.1088/1752-7155/8/2/027109.
|
[38] |
Kim YS,Maruvada P,Milner JA.Metabolomics in biomarker discovery:future uses for cancer prevention[J].Future Oncol,2008,4(1):93-102.
|
[39] |
Ewald N,Schaller M,Bayer M,et al.Fecal pyruvate kinase-M2(tumor M2-PK)measurement:a new screening concept for colorectal cancer[J].Anticancer Res,2007,27(4A):1949-1952.
|
[40] |
He WQ,Qian XP,Liu BR.STAT3 and individualized treatment of tumors[J].J Med Postgraduates(医学研究生学报),2009,22(9):981-983.
|
[41] |
Holmes E,Wilson I,Nicholson J.Metabolic phenotyping in health and disease[J].Cell,2008,134(5):714-717.
|
[42] |
Murphey LJ,Williams MK,Sanchez SC,et al.Quantification of the major urinary metabolite of PGE2 by a liquid chromatographic/mass spectrometric assay:determination of cyclooxygenase-specific PGE2 synthesis in healthy humans and those with lung cancer[J].Anal Biochem,2004,334(2):266-275.
|
[43] |
Wilson ID.Drugs,bugs,and personalized medicine:Pharmacometabonomics enters the ring[J].PNAS,2009,106(34):14187-14188.
|
[44] |
Kwon YK,Jung YS,Park JC,et al.Characterizing the effect of heavy metal contamination on marine mussels using metabolomics[J].Mar Pollut Bull,2012,64(9):1874-1879.
|
[1] | WANG Shanshan, LIANG En, WANG Xiaoling, MEI Dong, WANG Zengming, ZHENG Aiping. Current situation and prospect of 3D printing technology in pharmaceutical preparations[J]. Journal of China Pharmaceutical University, 2023, 54(1): 15-22. DOI: 10.11665/j.issn.1000-5048.20221130002 |
[2] | ZHANG Xue, OUYANG Huizhi, XU Wei, WANG Xiaoying. Effect of celastrol combined medication on the inhibition of HepG2 cell proliferation[J]. Journal of China Pharmaceutical University, 2020, 51(2): 185-192. DOI: 10.11665/j.issn.1000-5048.20200209 |
[3] | CAI Ming, SHU Bin, SHAO Qing, YUAN Yanjuan, ZHANG Yutang, QIAO Hongqun, LIU Jing. Embryo-fetal development toxicity of carenoprazan hydrochloride[J]. Journal of China Pharmaceutical University, 2018, 49(6): 725-730. DOI: 10.11665/j.issn.1000-5048.20180614 |
[4] | XING Xiaoqing, BU Xiumin, CHU Yanan, ZOU Bingjie, SONG Qinxin, ZHOU Guohua. Genotype method for SNPs related to individualized aspirin treatment based on pyrosequencing technology[J]. Journal of China Pharmaceutical University, 2017, 48(5): 577-582. DOI: 10.11665/j.issn.1000-5048.20170512 |
[5] | SHAO Feng, LIU Linsheng, A Jiye. Gas chromatography time-of-flight mass spectrometry based metabolomic approach to evaluate acute toxicity of triptolide in rats[J]. Journal of China Pharmaceutical University, 2014, 45(6): 703-709. DOI: 10.11665/j.issn.1000-5048.20140616 |
[6] | DING Yan-wei, LI Zuo-kui, ZHAO Hua, ZHANG Jian-xin, LI Bao-qiu. Toxicity of glufosfamide in Beagle dogs following intravenous injection[J]. Journal of China Pharmaceutical University, 2009, 40(6): 535-538. |
[7] | Study on Long-term Toxicity of Recombinant Human Acidic Fibroblast Growth Factor in Rabbits[J]. Journal of China Pharmaceutical University, 2003, (1): 48-52. |
[8] | The Toxicity and Pharmacokinetics of Cantharidin[J]. Journal of China Pharmaceutical University, 2002, (5): 40-43. |
[9] | Effect of L-Asparaginase,Proliposome on Toxicity in Mice and Experimental Tumor[J]. Journal of China Pharmaceutical University, 2001, (1): 69-71. |
[10] | Veinal Toxicity Study of Gatifloxacin in Beagle Dogs[J]. Journal of China Pharmaceutical University, 2000, (5): 63-68. |