• 中国精品科技期刊
  • 中国高校百佳科技期刊
  • 中国中文核心期刊
  • 中国科学引文数据库核心期刊
Advanced Search
YU Shule, MA Lin, WU Zhengfeng, ZHAO Shouxun, WANG Lei, YE Wencai, ZHANG Jian, YIN Zhiqi. Non-C21 steroids from the Rhizome of Cynanchum stauntonii[J]. Journal of China Pharmaceutical University, 2015, 46(4): 426-430. DOI: 10.11665/j.issn.1000-5048.20150407
Citation: YU Shule, MA Lin, WU Zhengfeng, ZHAO Shouxun, WANG Lei, YE Wencai, ZHANG Jian, YIN Zhiqi. Non-C21 steroids from the Rhizome of Cynanchum stauntonii[J]. Journal of China Pharmaceutical University, 2015, 46(4): 426-430. DOI: 10.11665/j.issn.1000-5048.20150407
shu

Non-C21 steroids from the Rhizome of Cynanchum stauntonii

More Information
    Graphical Abstract
    • Abstract
  • Twelve compounds were isolated and purified from ethyl acetatefraction of Cynanchum stauntonii by silica gel, Sephadex LH-20 and ODS column chromatography. Their structures were identified by spectral techniques and physicochemical properties as syringaresinol( 1 ), (-)-(7R, 7′R, 7″R, 8S, 8′S, 8″S)-4′, 4″-dihydroxy-3, 3′, 3″, 5-tetramethoxy-7, 9′ ∶7′, 9-diepoxy-4, 8″-oxy-8, 8′-sesquineolignan-7″, 9″-diol( 2 ), prinsepiol( 3 ), 4-hydroxyacetophenone( 4 ), baishouwubenzophenone( 5 ), 2, 4-dihydroxyacetophenone( 6 ), benzoic acid( 7 ), 1, 4-benzenediol( 8 ), 6-O-［E］-sinapoyl-α-D-glucopyranoside( 9a ), 6-O-［E］-sinapoyl-β-D-glucopyranoside( 9b ), 1-O-methyl-α-D-cymadropyranoside( 10 ), β-daucosterol( 11 ), and β-sitosterol( 12 ). Compounds 1 - 3 , 5 and 7 - 11 were firstly isolated from this plant.
    • FullText(HTML)
    • References (18)
  • [1]
    Ma YL,Fu HM,Fang J.Recent 10 years researches on Cynanchum stuntonii and other plants of Cynanchum Linn.[J].J Med Pharm Chin Minorities(中国民族医药杂志),2003,(65):318-322.
    [2]
    Liao YH. The difference between Cynanchum stuntonii and Cynanchum atratum Bunge.[J].J Prac Tradit Chin Med(实用中医药杂志),2008,24(5):326-327.
    [3]
    Liang AH,Xue BY,Yang Q,et al.The difference of the pharmacological activitives between Cynanchum stuntonii and Cynanchum atratum Bunge.[J].Chin J Chin Mater Med(中国中药杂志),1996,20(10):622-625.
    [4]
    Takashi N,Koji H,Hiroshi M.The structures of Glaucogenin A,Glaucogenin B,and Glaucogenin C-mono-D-thevetoside from Chinese drug“Pai-ch′ien”Cynanchum glaucescens(Decne.)Hand.-Mazz.[J].Tetrahedron Lett,1982,23(7):757-760.
    [5]
    Takashi N, Koji H, Hiroshi M. Studies on the constituents of Asclepiadaceae plants.The structures of three new Glaucosides,Glaucoside-H,-I and -J from the Chinese drug“Pai-ch′ien″ Cynanchum glaucescens(Decne.)Hand.-Mazz.[J].Chem Pharm Bult,1983,31(7):2244-2253.
    [6]
    YuJQ,DengAJ,Qin HL.Nine new steroidal glycosides from the roots of Cynanchum stauntonii[J].Steroids,2013,78:79-90.
    [7]
    Huang F,Fang Y,Zheng Q,et al.The antithrombotic activity of Cynanchum stauntonii[J].Zhejiang J Integr Tradit Chin West Med(浙江中西医结合杂志),2012,22(7):574-575.
    [8]
    Shen YQ,Zhang MF,Zhu ZP.The analgesics,anti-inflammatoryand antithrombotic activities of Cynanchum stauntonii[J].Chin Pharm(中国药房),2001,12(1):15-16.
    [9]
    Zhang M,Wang JS,Luo J,et al.Glaucogenin E,a new C21steroid from Cynanchum stauntonii[J].Nat Prod Res,2013,27(2):176-180.
    [10]
    Yu Y,Gao H,Dai Y.A new lignan from Gardenia jasminoides[J].Chin Tradit Herb Drug(中草药),2010,41(4):509-514.
    [11]
    Liang X, Zhu CG, Li YR, et al. Lignans and neolignans from Sinocalamus affinis and their absolute configurations[J].J Nat Prod,2011,74:1188-1200.
    [12]
    Piccinelli AL,Arana S,Caceres A,et al.New lignans from the roots of Valeriana prionophylla with antioxidative andvasorelaxantactivities[J].J Nat Prod,2004,67(7):1135-1140.
    [13]
    Li LB,He X,Wen XP.Studies on chemical constituents of Saussurea lancieps Hand.-Mazz.[J].Lishizhen Med Mater Med Res(时珍国医国药),2013,24(1):5-7.
    [14]
    Zhao YB,Ren HY,Zuo GY,et al.Component analysis of extract from Cynanchum otophyllum Schneid.[J].Med J Nat Defend Forces Southwest China(西南国防医药),2009,19(10):961-965.
    [15]
    Jia L,Bi YF,Jing LL,et al.Study chemical constituents of Urena procumbens L.[J].Chin Pharm J(中国药学杂志),2010,45(14):1054-1056.
    [16]
    Zhang JJ,Wang J,Xue J,et al.Chemical constituents from the stems and leaves of Sedum aizoon L.[J].J Shenyang Pharm Univ(沈阳药科大学学报),2010,27(8):635-638.
    [17]
    Lou HX,Li X,Zhu TR,et al.Sinapic acid esters and a phenolic glycoside from Cynanchum hancockianum[J].Phytochem,1993,32(5):1283-1286.
    [18]
    Keiji W,Koji H,Hiroshi M,et al.Studies on the constituents of Asclepiadaceae plants.L.Two new ologoglycosides,cynanchoside C2 and cynanchoside C1,from Cynanchum caudatum Max.[J].Chem Pharm Bult,1982,30:3500-3504.
    • Related Articles

  • Related Articles

    [1]LI Linzhen, WEI Xi, LIU Lu, LI Yongjun, LIANG Jingyu. Chemical constituents from the stems of Clerodendrum trichotomum Thunb.[J]. Journal of China Pharmaceutical University, 2019, 50(5): 544-548. DOI: 10.11665/j.issn.1000-5048.20190506
    [2]LIN Qinghua, XU Jian, FENG Feng. Chemical constituents from the stems of Picrasma quassioides Bennet[J]. Journal of China Pharmaceutical University, 2017, 48(6): 675-679. DOI: 10.11665/j.issn.1000-5048.20170607
    [3]XU Yunhui, JIANG Xueyang, XU Jian, JIANG Renwang, ZHANG Jie, XIE Zijian, FENG Feng. Chemical constituents from Callicarpa kwangtungensis Chun[J]. Journal of China Pharmaceutical University, 2016, 47(3): 299-302. DOI: 10.11665/j.issn.1000-5048.20160309
    [4]MA Lin, ZHANG Rongfei, YU Shule, WU Zhengfeng, ZHAO Shouxun, Wang Lei, YE Wencai, ZHANG Jian, YIN Zhiqi. Chemical constituents of Fructus Gleditsiae Abnormalis[J]. Journal of China Pharmaceutical University, 2015, 46(2): 188-193. DOI: 10.11665/j.issn.1000-5048.20150209
    [5]LI Linzhen, WANG Menghua, SUN Jianbo, LIANG Jingyu. Chemical constituents from Aletris spicata[J]. Journal of China Pharmaceutical University, 2014, 45(2): 175-177. DOI: 10.11665/j.issn.1000-5048.20140208
    [6]CHANG Bo, XIAO Linjing, ZHANG Jian, ZHAO Shouxun, YE Wencai, YIN Zhiqi. Chemical constituents from Abies ernestii var.salouenensis[J]. Journal of China Pharmaceutical University, 2014, 45(1): 43-47. DOI: 10.11665/j.issn.1000-5048.20140107
    [7]MENG Fancheng, WANG Lei, ZHANG Jian, YIN Zhiqi, ZHANG Qingwen, YE Wencai. Non-alkaloid chemical constituents from the rhizome of Coptis teeta[J]. Journal of China Pharmaceutical University, 2013, 44(4): 307-310. DOI: 10.11665/j.issn.1000-5048.20130404
    [8]YIN Minmin, YIN Zhiqi, ZHANG Jian, WANG Lei, YE Wencai. Chemical constituents from ethyl acetate extract of Cynanchum otophyllum Schneid.[J]. Journal of China Pharmaceutical University, 2013, 44(3): 213-218. DOI: 10.11665/j.issn.1000-5048.20130305
    [9]LI Jiu-hui, CHEN Guang-ying, HAN Chang-ri, MO Zheng-rong, SONG Xiao-ping. Chemical constituents from the stems of Vatica mangachpoi Blanco[J]. Journal of China Pharmaceutical University, 2012, 43(1): 25-27.
    [10]Chemical constituents from Senecio nemorensis.[J]. Journal of China Pharmaceutical University, 2010, 41(1): 26-28.

Catalog

    Get Citation
    PDF
    XML
    Article views (1533) PDF downloads (1996) Cited by()
    Turn off MathJax
    Article Contents
    Abstract
    References
    Related Articles

    Copyright © Journal of China Pharmaceutical University苏ICP备12050101号-2

    Address：24 Tongjia Lane, Nanjing City, Jiangsu Province （210009）Tel: 025-83271566E-mail: xuebao@cpu.edu.cn

    Supported by: Beijing Renhe Information Technology Co., Ltd.  Baidu Analytics

    Total visits：302641

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return