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YU Shule, MA Lin, WU Zhengfeng, ZHAO Shouxun, WANG Lei, YE Wencai, ZHANG Jian, YIN Zhiqi. Non-C21 steroids from the Rhizome of Cynanchum stauntonii[J]. Journal of China Pharmaceutical University, 2015, 46(4): 426-430. DOI: 10.11665/j.issn.1000-5048.20150407
Citation: YU Shule, MA Lin, WU Zhengfeng, ZHAO Shouxun, WANG Lei, YE Wencai, ZHANG Jian, YIN Zhiqi. Non-C21 steroids from the Rhizome of Cynanchum stauntonii[J]. Journal of China Pharmaceutical University, 2015, 46(4): 426-430. DOI: 10.11665/j.issn.1000-5048.20150407
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Non-C21 steroids from the Rhizome of Cynanchum stauntonii

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  • Twelve compounds were isolated and purified from ethyl acetatefraction of Cynanchum stauntonii by silica gel, Sephadex LH-20 and ODS column chromatography. Their structures were identified by spectral techniques and physicochemical properties as syringaresinol( 1 ), (-)-(7R, 7′R, 7″R, 8S, 8′S, 8″S)-4′, 4″-dihydroxy-3, 3′, 3″, 5-tetramethoxy-7, 9′ ∶7′, 9-diepoxy-4, 8″-oxy-8, 8′-sesquineolignan-7″, 9″-diol( 2 ), prinsepiol( 3 ), 4-hydroxyacetophenone( 4 ), baishouwubenzophenone( 5 ), 2, 4-dihydroxyacetophenone( 6 ), benzoic acid( 7 ), 1, 4-benzenediol( 8 ), 6-O-［E］-sinapoyl-α-D-glucopyranoside( 9a ), 6-O-［E］-sinapoyl-β-D-glucopyranoside( 9b ), 1-O-methyl-α-D-cymadropyranoside( 10 ), β-daucosterol( 11 ), and β-sitosterol( 12 ). Compounds 1 - 3 , 5 and 7 - 11 were firstly isolated from this plant.
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