Chemical constituents of<i> Adina rubella</i>

ZHANG Lei; GAO Ying; JIANG Yuntao; RUAN Shanming; SHEN Minhe; WANG Hao

doi:10.11665/j.issn.1000-5048.20150507

Journal of China Pharmaceutical University > 2015 > 46(5): 556-560. > DOI: 10.11665/j.issn.1000-5048.20150507

ZHANG Lei, GAO Ying, JIANG Yuntao, RUAN Shanming, SHEN Minhe, WANG Hao. Chemical constituents of Adina rubella[J]. Journal of China Pharmaceutical University, 2015, 46(5): 556-560. DOI: 10.11665/j.issn.1000-5048.20150507

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Chemical constituents of Adina rubella

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From the ethanol extract of Adina rubella, twelve compounds were isolated by silica gel and ODS column chromatography. Their structures were identified by spectroscopic analysis as: 5, 7-dihydroxy-2-methylchromone-7-O-β-D-glucopyranoside( 1 ), scopolin( 2 ), (+)-lyoniresinol-3a-O-β-D-glucopyranoside( 3 ), (6S, 7R, 8R)-7a-［(β-D-glucopyranosyl)oxy］ lyoniresinol( 4 ), harman-3-carboxylic acid( 5 ), lyaloside( 6 ), 3-oxoquinovid acid( 7 ), oleanolic acid( 8 ), 3-acetyl oleanolic acid( 9 ), quinovic acid 3-O-β-D-glucopyranosyl-28-O-β-L-rhamnopyranosyl ester( 10 ), quinovic acid 3-O-β-D-glucopyranosiyl-28-O-β-D-glucopyranosyl ester( 11 )and pyrocincholic acid 3-O-α-L-rhamnopyranosyl-28-［β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosyl］ ester( 12 ). Compounds 3, 4, 6, 8-10 were isolated from this plant for the first time.
- Rubiaceae,
- Adina rubella,
- chemical constituents,
- isolation,
- identification

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