Citation: | LU Xiaolin, ZHENG Ying, QIU Yang, ZHOU Xiang, LU Tao. Small conjugate-based theranostic agents:a tumour microenvironment responsive approach for cancer therapy[J]. Journal of China Pharmaceutical University, 2016, 47(6): 629-638. DOI: 10.11665/j.issn.1000-5048.20160601 |
[1] |
Xie J,Lee S,Chen XY.Nanoparticle-based theranostic agents[J].Adv Drug Deliv Rev,2010,62(11):1064-1079.
|
[2] |
Kelkar SS, Reineke TM. Theranostics: combining imaging and therapy[J].Bioconjug Chem, 2011,22(10):1879-1903.
|
[3] |
Nie S,Xing Y,Kim GJ,et al.Nanotechnology applications in cancer[J].Annu Rev Biomed Eng,2007,9(8):257-288.
|
[4] |
Lim EK, Kim T, Paik S, et al. Nanomaterials for theranostics:recent advances and future challenges[J].Chem Rev,2015,115(1):327-394.
|
[5] |
Jokerst JV,Gambhir SS.Molecular imaging with theranostic nanoparticles[J].Acc Chem Res,2011,44(10):1050-1060.
|
[6] |
Dong X,Gu YQ.Application of optical molecular imaging technology in the diagnosis and treatment of diseases[J].J China Pharm Univ(中国药科大学学报),2014,45(2):145-152.
|
[7] |
Zhou LZ,Wu XR,Chen L.Pharmacokinetics of magnetic nanoparticles as drug carrier and their applications in cancer diagnosis and therapy[J].J China Pharm Univ(中国药科大学学报),2003,34(3):279-282.
|
[8] |
Sies H.Glutathione and its role in cellular functions[J].Free Radic Biol Med,1999,27(9/10):916-921.
|
[9] |
Gregory RJ,Kirsten MT,McEwan J,et al.Vitamin-mediated targeting as a potential mechanism to increase drug uptake by tumours[J].J Inorg Biochem,2004,98(10):1625-1633.
|
[10] |
Santra S,Kaittanis C,Santiesteban OJ,et al.Cell-specific,activatable,and theranostic prodrug for dual-targeted cancer imaging and therapy[J].J Am Chem Soc,2011,133(41):16680-16688.
|
[11] |
Yang Z,Lee JH,Jeon HM,et al.Folate-based near-infrared fluorescent theranostic gemcitabine delivery[J].J Am Chem Soc,2013,135(31):11657-11662.
|
[12] |
Bildstein L,Dubernet C,Couvreur P.Prodrug-based intracellular delivery of anticancer agents[J].Adv Drug Deliv Rev,2011,63(1/2):3-23.
|
[13] |
Maiti S,Park N,Han JH,et al.Gemcitabine-coumarin-biotin conjugates:a target specific theranostic anticancer prodrug[J].J Am Chem Soc,2013,135(11):4567-4572.
|
[14] |
Bhuniya S,Lee MH,Jeon HM,et al.A fluorescence off-on reporter for real time monitoring of gemcitabine delivery to the cancer cells[J].Chem Commun,2013,49(64):7141-7143.
|
[15] |
Kim T,Jeon HM,Le HT,et al.A biotin-guided fluorescent-peptide drug delivery system for cancer treatment[J].Chem Commun,2014,50(57):7690-7693.
|
[16] |
Bhuniya S,Maiti S,Kim EJ,et al.An activatable theranostic for targeted cancer therapy and imaging[J].Angew Chem Int Ed,2014,53(17):4469-4474.
|
[17] |
Vineberg JG,Zuniga ES,Kamath A,et al.Design,synthesis,and biological evaluations of tumor-targeting dual-warhead conjugates for a taxoid-camptothecin combination chemotherapy[J].J Med Chem,2014,57(13):5777-5791.
|
[18] |
Vineberg JG, Wang T, Zuniga ES, et al. Design, synthesis, and biological evaluation of theranostic vitamin-linker-taxoid conjugates[J].J Med Chem,2015,58(5):2406-2416.
|
[19] |
Lee MH,Kim JY,Han JH,et al.Direct fluorescence monitoring of the delivery and cellular uptake of a cancer-targeted RGD peptide-appended naphthalimide theragnostic prodrug[J].J Am Chem Soc,2012,134(30):12668-12674.
|
[20] |
Dongbang S,Jeon HM,Lee MH,et al.Camptothecin delivery into hepatoma cell line by galactose-appended fluorescent drug deli-very system[J].RSC Adv,2014,4:18744-18748.
|
[21] |
Wu X,Sun X,Guo Z,et al.In vivo and in situ tracking cancer chemotherapy by highly photostable NIR fluorescent theranostic prodrug[J].J Am Chem Soc,2014,136(9):3579-3588.
|
[22] |
Wu J,Huang R,Wang CC,et al.Thiol-inducible direct fluorescence monitoring of drug release[J].Org Biomol Chem,2013,11:580-585.
|
[23] |
Dickinson BC,Chang CJ.Chemistry and biology of reactive oxygen species in signaling or stress responses[J].Nat Chem Biol,2011,7(8):504-511.
|
[24] |
Lippert AR,Van de Bittner GC,Chang CJ.Boronate oxidation as a bioorthogonal reaction approach for studying the chemistry of hydrogen peroxide in living systems[J].Acc Chem Res,2011,44(9):793-804.
|
[25] |
Kim EJ,Bhuniya S,Lee H,et al.An activatable prodrug for the treatment of metastatic tumors[J].J Am Chem Soc,2014,136(39):13888-13894.
|
[26] |
Kumar R,Han J,Lim HJ,et al.Mitochondrial induced and self-monitored intrinsic apoptosis by antitumor theranostic prodrug:in vivo imaging and precise cancer treatment[J].J Am Chem Soc,2014,136(51):17836-17843.
|
[27] |
Manchun S,Dass CR,Sriamornsak P.Targeted therapy for cancer using pH- responsive nanocarrier systems[J].Life Sci,2012,90(11/12):381-387.
|
[28] |
Song QL,Li P.Research progress of pH-sensitive material in pharmaceutical preparation[J].China J Hosp Pharm(中国医院药学杂志),2011,31:240-243.
|
[29] |
Li SY,Liu LH,Jia HZ,et al.A pH-responsive prodrug for real-time drug release monitoring and targeted cancer therapy[J].Chem Commun,2014,50(80):11852-11855.
|
[1] | ZHAO Xiaomei, WANG Xin, JI Xia, Zhang Jing, ZHANG Hua, HU Guoqiang. Synthesis and antitumor activity of heteroatom-substituted azulenes derivatives of 1,2-benzothiazine[J]. Journal of China Pharmaceutical University, 2024, 55(5): 634-638. DOI: 10.11665/j.issn.1000-5048.2023120503 |
[2] | SUN Dongyu, GONG Jingxu, LI Xuwen, HAN Guanying, GUO Yuewei. Studies on methyl xestopongoate analogues:design, synthesis and antitumor activities[J]. Journal of China Pharmaceutical University, 2018, 49(4): 413-421. DOI: 10.11665/j.issn.1000-5048.20180405 |
[3] | LI Mingtao, XU Dan, XUE Wenjun, YOU Qidong, SUN Liping. Design, synthesis and antitumor activities of oxazolo[5, 4-d]pyrimidine derivatives[J]. Journal of China Pharmaceutical University, 2017, 48(4): 425-431. DOI: 10.11665/j.issn.1000-5048.20170406 |
[4] | QIAO Yixue, MOU Yi, HUANG Zhangjian, AI Yong, KANG Fenghua, LAI Yisheng, ZHANG Yihua. Synthesis and antitumor activities of novel CDDO-Me analogues[J]. Journal of China Pharmaceutical University, 2015, 46(3): 289-293. DOI: 10.11665/j.issn.1000-5048.20150305 |
[5] | MAO Chunfang, XU Chenjun, WANG Xuemin, LI Xianghua, ZHANG Wei, WANG Xinyang, LING Yong. Design, synthesis and antitumor activity of farnesylthiosalicylamide derivatives[J]. Journal of China Pharmaceutical University, 2015, 46(2): 162-168. DOI: 10.11665/j.issn.1000-5048.20150204 |
[6] | HU Kun, ZHOU Anfei, JIANG Hefei, XU Yuanyuan, HUANG Qianhui, YANG Jie, CHEN Xin, REN Jie. Synthesis and antitumor activities of podophyllotoxin derivatives[J]. Journal of China Pharmaceutical University, 2014, 45(1): 33-38. DOI: 10.11665/j.issn.1000-5048.20140105 |
[7] | CHENG Keguang, CHU Xiangwu, LIU Guanyan, SU Chunhua, DENG Shengping, PAN Hongmei. Synthesis and antitumor activities of 3-substituted estradiol-pyrimidine derivatives[J]. Journal of China Pharmaceutical University, 2014, 45(1): 26-32. DOI: 10.11665/j.issn.1000-5048.20140104 |
[8] | LIU Dexiu, PAN Huaying, SHI Hui, HUANG Xiaoying, LOU Hongxiang. Synthesis and antitumor activity of a novel bisbibenzyl derivative[J]. Journal of China Pharmaceutical University, 2013, 44(6): 515-519. DOI: 10.11665/j.issn.1000-5048.20130605 |
[9] | HU Kun, XU Hua-jin, XIN Wen-qun, CHEN Xin, REN Jie. Synthesis and antitumor activity of nitrogen mustard derivatives of formononetin[J]. Journal of China Pharmaceutical University, 2012, 43(2): 113-119. |
[10] | ZHA Xiao-ming, ZHANG Fei-ran, SHAN Jia-qi, CHEN Yan-ke, ZHANG Yi-hua, LIU Jun, SUN Hong-bin. Synthesis and in vitro antitumor activities of novel soladulcidine derivatives[J]. Journal of China Pharmaceutical University, 2010, 41(6): 493-498. |