Advances of new excipients and technique in colon-specific preparations

SU Shina; LYU Zhufen; LIANG Chaofeng; LU Kewei; HUANG Yunran; CHEN Yanzhong

doi:10.11665/j.issn.1000-5048.20170217

Journal of China Pharmaceutical University > 2017 > 48(2): 242-250. > DOI: 10.11665/j.issn.1000-5048.20170217

SU Shina, LYU Zhufen, LIANG Chaofeng, LU Kewei, HUANG Yunran, CHEN Yanzhong. Advances of new excipients and technique in colon-specific preparations[J]. Journal of China Pharmaceutical University, 2017, 48(2): 242-250. DOI: 10.11665/j.issn.1000-5048.20170217

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Advances of new excipients and technique in colon-specific preparations

SU Shina^1,2,3,
LYU Zhufen^1,2,
LIANG Chaofeng^3,4,5,6,
LU Kewei^4,5,6,
HUANG Yunran³,
CHEN Yanzhong^1,2,3

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Abstract

Abstract

The oral colon-specific drug delivery system(OCDDS)has gained more attention from investigators in recent years since it can increase local drug concentration and reduce dosage and side effects. The type of colon-specific drug delivery system consists of enzyme dependent, pH dependent, time dependent, pressure dependent system and CODEDS^TM. The development of many new materials and technology is very important for the preparation of new type of precise positioning colon-specific preparation. This article summarizes the advances in excipients and technique for oral colon-specific drug delivery system in recent years. It may provide a reference and a basis for the researchers concerned.
- oral colon-specific drug delivery system,
- excipients,
- technique,
- application

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