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LI Dan, FU Mian, QIAN Hai, HUANG Wenlong. Phenylboronic acid-based glucose-responsive materials:synthesis and applications in insulin delivery[J]. Journal of China Pharmaceutical University, 2017, 48(3): 259-267. DOI: 10.11665/j.issn.1000-5048.20170302
Citation: LI Dan, FU Mian, QIAN Hai, HUANG Wenlong. Phenylboronic acid-based glucose-responsive materials:synthesis and applications in insulin delivery[J]. Journal of China Pharmaceutical University, 2017, 48(3): 259-267. DOI: 10.11665/j.issn.1000-5048.20170302
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Phenylboronic acid-based glucose-responsive materials:synthesis and applications in insulin delivery

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    • Abstract
  • Glucose-sensitive materials have attracted much interest due to their potential application in diabetes treatment in recent years. Phenylboronic acid-based glucose-responsive polymers, which possess continuous glucose sensitivity and good stability, have been most widely used in self-regulated insulin delivery. This review covers the recent advances in PBA-functionalized nanogels(microgels), micelles, vesicles and nanoparticles. Synthesis and application of these nanomaterials are discussed. With the development of PBA-regulated polymers, these nanomaterials will migrate from laboratory to clinical use in the near future.
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