Citation: | DU Xiaodian, SUN Fumou, YUAN Minne, WANG Fei, LIU Yali, SHANG Pengzhao, WANG Min, ZHANG Juan. Antitumor efficacy of bispecific antibody mAb04-MICA to human leukemia cell K562 in vitro and in vivo[J]. Journal of China Pharmaceutical University, 2018, 49(1): 117-124. DOI: 10.11665/j.issn.1000-5048.20180117 |
[1] |
Ferrara N,Kerbel RS.Angiogenesis as a therapeutic target[J].Nature,2005,438(7070):967-974.
|
[2] |
Carmeliet P,Jain RK.Molecular mechanisms and clinical applications of angiogenesis[J].Nature,2011,473(7347):298-307.
|
[3] |
Jr RR.Vascular endothelial growth factor(VEGF)signaling in tumor progression[J].Crit Rev Oncol Hematol,2007,62(3):179-213.
|
[4] |
Musumeci F,Radi M,Brullo C,et al.Vascular endothelial growth factor(VEGF)receptors:drugs and new inhibitors[J].J Med Chem,2012,55(24):10797-10822.
|
[5] |
Xu WW,Li B,Lam AK,et al.Targeting VEGFR1- and VEGFR2-expressing non-tumor cells is essential for esophageal cancer therapy[J].Oncotarget,2015,6(3):1790-1805.
|
[6] |
Fuchs CS,Tabernero J,Tomáek J,et al.Biomarker analyses in REGARD gastric/GEJ carcinoma patients treated with VEGFR2-targeted antibody ramucirumab[J].Br J Cancer,2016,115(8):974-982.
|
[7] |
Fuchs CS,Tomasek J,Yong CJ,et al.Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma(REGARD):an international,randomised,multicentre,placebo-controlled,phase 3 trial[J].Lancet,2014,383(9911):31-39.
|
[8] |
Saif MW,Elfiky A,Salem RR.Gastrointestinal perforation due to bevacizumab in colorectal cancer[J].Ann Surg Oncol,2007,14(6):1860-1869.
|
[9] |
Kappers MH,Smedts FM,Horn T,et al.The vascular endothelial growth factor receptor inhibitor sunitinib causes a preeclampsia-like syndrome with activation of the endothelin system[J].Hypertension,2011,58(2):295-302.
|
[10] |
Cho HM,Rosenblatt JD,Tolba K,et al.Delivery of NKG2D ligand using an anti-HER2 antibody-NKG2D ligand fusion protein results in an enhanced innate and adaptive antitumor response[J].Cancer Res,2010,70(24):10121-10130.
|
[11] |
Veluchamy JP, Heeren AM, Spanholtz J, et al. High-efficiency lysis of cervical cancer by allogeneic NK cells derived from umbilical cord progenitors is independent of HLA status[J].Cancer Immunol Immunother,2017,66(1):51.
|
[12] |
Lopez-Soto A,Huergo-Zapico L,Acebes-Huerta A,et al.NKG2D signaling in cancer immunosurveillance[J].Int J Cancer,2015,136(8):1741-1750.
|
[13] |
Isernhagen A, Malzahn D, Viktorova E, et al. The MICA-129 dimorphism affects NKG2D signaling and outcome of hematopoietic stem cell transplantation[J].EMBO Mol Med,2015,7(11):1480-1502.
|
[14] |
Wu JD,Atteridge CL,Wang X,et al.Obstructing shedding of the immunostimulatory MHC class I chain-related gene B prevents tumor formation[J].Clin Cancer Res,2009,15(2):632-640.
|
[15] |
Xie W,Fang L,Wang Y,et al.VEGFR2 targeted antibody fused with MICA stimulates NKG2D mediated immunosurveillance and exhibits potent anti-tumor activity against breast cancer[J].Oncotarget,2016,7(13):16445-16461.
|
[16] |
Ren X,Xie W,Wang Y,et al.VEGFR2-targeted fusion antibody improved NK cell-mediated immunosurveillance against K562 cells[J].Immunol Res,2016,64(4):1060-1070.
|
[17] |
Zhou YJ,Dou RK,Bi ZF,et al.Promotion of apoptosis in leukemia K562 cells by natural plant-derived antimicrobial solution(PAMs)[J].J China Pharma Univ(中国药科大学学报),2015,46(6):712-718.
|
[18] |
Shi L,Zhang J,Wu P,et al.Discovery and identification of potential biomarkers of pediatric acute lymphoblastic leukemia[J].Proteome Sci,2009,7(1):7.
|
[19] |
Xie W,Li D,Zhang J,et al.Generation and characterization of a novel human IgG1 antibody against vascular endothelial growth factor receptor 2[J].Cancer Immunol Immunother,2014,63(9):877-888.
|
[20] |
Acheampong DO,Tang M,Wang Y,et al.A novel fusion antibody exhibits antiangiogenic activity and stimulates NK cell-mediated immune surveillance through fused NKG2D ligand[J].J Immunother,2017,40(3):94-103.
|
[21] |
Wang T,Sun F,Xie W,et al.A bispecific protein rG7S-MICA recruits natural killer cells and enhances NKG2D-mediated immunosurveillance against hepatocellular carcinoma[J].Cancer Lett,2016,372(2):166-178.
|
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