Role of non-coding RNA in pulmonary arterial hypertension

XU Yi; YU Feng; LIU Yun

doi:10.11665/j.issn.1000-5048.20190115

Journal of China Pharmaceutical University > 2019 > 50(1): 107-112. > DOI: 10.11665/j.issn.1000-5048.20190115

XU Yi, YU Feng, LIU Yun. Role of non-coding RNA in pulmonary arterial hypertension[J]. Journal of China Pharmaceutical University, 2019, 50(1): 107-112. DOI: 10.11665/j.issn.1000-5048.20190115

Citation:

XU Yi, YU Feng, LIU Yun. Role of non-coding RNA in pulmonary arterial hypertension[J]. Journal of China Pharmaceutical University, 2019, 50(1): 107-112. DOI: 10.11665/j.issn.1000-5048.20190115

Citation:

XU Yi, YU Feng, LIU Yun. Role of non-coding RNA in pulmonary arterial hypertension[J]. Journal of China Pharmaceutical University, 2019, 50(1): 107-112. DOI: 10.11665/j.issn.1000-5048.20190115

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Role of non-coding RNA in pulmonary arterial hypertension

XU Yi^1,2,
YU Feng²,
LIU Yun¹

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Abstract

Abstract

Non-coding RNA(ncRNA), a group of RNAs including microRNA, lncRNA, ceRNA, etc. , has multiple functions without protein-coding. It can regulate gene expression through epigenetics by various aspects such as transcription and post-transcription regulation. Recently, a large number of studies have found that ncRNA can cause a variety of diseases, such as cardiovascular disease, cancer, pulmonary arterial hypertension(PAH)and so on. This paper reviews the research progress on the role of ncRNA in PAH formation to provide theoretical foundation for the treatment of PAH.
- non-coding RNA,
- pulmonary arterial hypertension,
- pathogenesis

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References

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