Research progress of inorganic nanomaterials in drug delivery system

ZHOU Yeshu; WANG Yanmei; ZHANG Beiyuan; WU Shuaicong; YANG Lei; YIN Lifang

doi:10.11665/j.issn.1000-5048.20200403

Journal of China Pharmaceutical University > 2020 > 51(4): 394-405. > DOI: 10.11665/j.issn.1000-5048.20200403

ZHOU Yeshu, WANG Yanmei, ZHANG Beiyuan, WU Shuaicong, YANG Lei, YIN Lifang. Research progress of inorganic nanomaterials in drug delivery system[J]. Journal of China Pharmaceutical University, 2020, 51(4): 394-405. DOI: 10.11665/j.issn.1000-5048.20200403

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Research progress of inorganic nanomaterials in drug delivery system

Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China

Funds: This study was supported by the National Natural Science Foundation of China (No.81603051, No.81673377 and No.81871477);the National Science and Technology Major Project for Drug Innovation (No.2017ZX09101001-004);the Natural Science Foundation of Jiangsu Province (No.BK20160760 and No.BK20170748); the Fundamental Research Funds for the Central Universities (No.2016ZPY015);and the “333” High Level Talents Cultivation Project of Jiangsu Province

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Received Date: November 17, 2019

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Abstract

Efficient and safe delivery of drugs, proteins or genes to the targeted sites has been the focus of pharmaceutical research. Inorganic nanomaterials are ideal materials for drug delivery systems due to their good stability, excellent biocompatibility and high drug loading capacity.Inorganic nanomaterials are ideal materials for drug delivery systems due to their good stability, high biocompatibility and excellent drug loading capacity. In this review, we started with reported researches and clinical trials to discuss the researches and clinical transformation of these inorganic nanoparticles in application of drug delivery, including carbon nanomaterials, silica nanoparticles, calcium nanomaterials, gold nanoparticles, magnetic nanoparticles, upconversion nanoparticles and quantum dots, providing theoretical reference for application of inorganic drug delivery carriers in the development of new drugs, looking to the prospects of inorganic nanomaterials in clinical application.
- inorganic nanomaterials,
- drug delivery,
- clinical transformation,
- nanotechnology,
- advances

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References

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