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LIN Lin, QI Xiaodong, LI Yongsu, YANG Yubo, YANG Minghua, CHEN Yi, KONG Lingyi, WANG Li. Identification of involatile chemical components from Moutai-flavored distiller’s grains[J]. Journal of China Pharmaceutical University, 2023, 54(4): 461-467. DOI: 10.11665/j.issn.1000-5048.2023040402
Citation: LIN Lin, QI Xiaodong, LI Yongsu, YANG Yubo, YANG Minghua, CHEN Yi, KONG Lingyi, WANG Li. Identification of involatile chemical components from Moutai-flavored distiller’s grains[J]. Journal of China Pharmaceutical University, 2023, 54(4): 461-467. DOI: 10.11665/j.issn.1000-5048.2023040402
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Identification of involatile chemical components from Moutai-flavored distiller’s grains

  • 1.

    Kweichow Moutai Co., Ltd., Zunyi 564501

  • 2.

    Laboratory of Natural Active Components and Pharmacodynamics Research, Pharmaceutical University, Nanjing 211198

  • 3.

    Kweichow Moutai Group, Zunyi 564501, China

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  • Received Date: April 03, 2023
  • Revised Date: May 29, 2023
    Graphical Abstract
    • Abstract
  • In order to study the involatile chemical components in Moutai-flavored distiller’s grains, the Moutai-flavored distiller’s grains were extracted with 75% ethanol, followed by extraction with petroleum ether, ethyl acetate, and n-butanol. Silica gel, ODS, sephadex LH-20, and preparative HPLC were used to separate and identify the petroleum ether and ethyl acetate layers.ESI-MS and NMR were used to identify the compounds, which were respectively identified as pentadecanoic acid (1), palmitic acid (2), trans-2-decenoic acid (3), n-nonyl octadecanoate (4), ethyl octadecanoate (5), ethyl linoleate (6), luric acid (7), 1, 3-dicaprylyl-2-linoleylglycerin (8), cyclic (phenylalanine-proline) (9), cyclo-(proline-leucine) (10), 3, 6-bis-(2-methylpropyl)-2,5-dione piperazine (11), 4-hydroxyphenethyl alcohol (12), 2,4-dihydroxybenzoic acid (13), stigmasterol (14), 2-furancarboxylic acid (15), valine (16), L-alanine acyl-L-proline (17), dihydroquercetin (18), 5, 7, 3'', 4''-tetrahydroxyflavonoids (19), quercetin (20), and naringenin (21). Compounds 1-21 were isolated from distiller’s grains for the first time.
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    • References (32)
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