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SHEN Jiamiao, CAI Juntao, LI Jieming, et al. Research progress on the mechanism of traditional Chinese medicine polysaccharides in preventing and treating kidney injury[J]. J China Pharm Univ, 2024, 55(4): 454 − 462. DOI: 10.11665/j.issn.1000-5048.2024051501
Citation: SHEN Jiamiao, CAI Juntao, LI Jieming, et al. Research progress on the mechanism of traditional Chinese medicine polysaccharides in preventing and treating kidney injury[J]. J China Pharm Univ, 2024, 55(4): 454 − 462. DOI: 10.11665/j.issn.1000-5048.2024051501
shu

Research progress on the mechanism of traditional Chinese medicine polysaccharides in preventing and treating kidney injury

  • 1.

    Academy of Chinese Medical Science, Henan University of Chinese Medicine, Zhengzhou 450046

  • 2.

    Henan Polysaccharide Research Center, Zhengzhou 450046

  • 3.

    Henan Key Laboratory of Chinese Medicine for Polysaccharides and Drugs Research, Zhengzhou 450046 , China

Funds: This study was supported by the Natural Science Foundation of Henan Province（No.232300421374）and the China Postdoctoral Science Foundation（No.2021M690936）
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  • Received Date: May 14, 2024
    Graphical Abstract
    • Abstract

  • Traditional Chinese medicine (TCM) polysaccharides are active polysaccharides extracted from Chinese herbal medicines, many of which exhibit specific biological activities. Modern research has revealed that polysaccharide components extracted from plants, animals, and algae have a significant role in improving kidney injury. Currently, drug therapy is the primary treatment for kidney injury, with few reports on the use of TCM polysaccharides. This review explores the therapeutic effects and mechanisms of TCM polysaccharides on diabetic nephropathy, nephritis, kidney stones, hypertension-induced kidney injury, chemical toxin-induced kidney injury, and drug-induced kidney injury. Additionally, it discusses the prospects for the development of TCM polysaccharides in this field to provide a reference for further research.

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