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Yang Qinghua, Zheng Chunen, Zeng Chaojun, Yu Rugu. UV Spectrophotometric and Colorimetric Determination of Ortho Dihydric phenolic Drugs Ⅳ. Determination of Isoprenaline Hydrochloride and It's Content in Aerosol[J]. Journal of China Pharmaceutical University, 1981, (1): 41-47.
Citation: Yang Qinghua, Zheng Chunen, Zeng Chaojun, Yu Rugu. UV Spectrophotometric and Colorimetric Determination of Ortho Dihydric phenolic Drugs Ⅳ. Determination of Isoprenaline Hydrochloride and It's Content in Aerosol[J]. Journal of China Pharmaceutical University, 1981, (1): 41-47.
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UV Spectrophotometric and Colorimetric Determination of Ortho Dihydric phenolic Drugs Ⅳ. Determination of Isoprenaline Hydrochloride and It's Content in Aerosol

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  • The ultraviolet spectrophotometric method and colorimetric method are used for thedetermination of isoprenaline hydrochlorid aerosol. The former is carried out bymeasuring absorbance at 279nm±mm. The absorption coefficient of isoprenaline isdetermined,E_(1cm)~(1%)279nm=112.8; The latter method is based on the reaction ofisoprenaline with sodium nitrite-sodium molybdate at alkaline medium forming a redcompound. By measuring the absorption of such red compound at 500±mm, it ispossible to determine the isoprenaline content in the sample. The concentration rangeof isoprenaline is between 4～40μg/ml, which is in agreement with Beer's laws.Theisoprenaline in the aerosol is also determined colorimetrically. Interferences to owning guaiphenesin and ascorbic acid are negligible.
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