Cao Mingzhu, Hu Shuchen, Li Minghua, Zhang Song. The Synthesis of Carboxylic Esters of Dihydroartemisinine[J]. Journal of China Pharmaceutical University, 1982, (1): 53-54.
Citation:
Cao Mingzhu, Hu Shuchen, Li Minghua, Zhang Song. The Synthesis of Carboxylic Esters of Dihydroartemisinine[J]. Journal of China Pharmaceutical University, 1982, (1): 53-54.
Cao Mingzhu, Hu Shuchen, Li Minghua, Zhang Song. The Synthesis of Carboxylic Esters of Dihydroartemisinine[J]. Journal of China Pharmaceutical University, 1982, (1): 53-54.
Citation:
Cao Mingzhu, Hu Shuchen, Li Minghua, Zhang Song. The Synthesis of Carboxylic Esters of Dihydroartemisinine[J]. Journal of China Pharmaceutical University, 1982, (1): 53-54.
The Synthesis of Carboxylic Esters of Dihydroartemisinine
Artemisinine is a new type of fast-acting suppresive antimalarial drug. Dihydroar-temisinine is its reduced product. We have prepared nine oarboxylio esters of dihvdroartemisinine for evaluation of their antimalarial potency. All the new compounds have been tested for suppressive antimalarial activity against p. herghei in mice, four Ⅰ、Ⅱ、Ⅲ、Ⅸ,) of them are superior to artemisinine.
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