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Dai Dezai, Li Jingyi, Yang Pengbin. DOPAMINERGIC SYSTEM IN RELATION TO SCOPOLAMINE -INDUCED ANAESTHESIA[J]. Journal of China Pharmaceutical University, 1984, (1): 53-56.
Citation: Dai Dezai, Li Jingyi, Yang Pengbin. DOPAMINERGIC SYSTEM IN RELATION TO SCOPOLAMINE -INDUCED ANAESTHESIA[J]. Journal of China Pharmaceutical University, 1984, (1): 53-56.
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DOPAMINERGIC SYSTEM IN RELATION TO SCOPOLAMINE -INDUCED ANAESTHESIA

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  • Both the load of large dose of L-DOPA in mice and injection of 6-hydroxy-dopamine into cerebral ventricles in rabbits 3 days before caused a prolonged anaesthetic period induced by scopolamine injected cerebroventrically(P<0.05).It was suggested that the dopaminergic system in the brain exerts certain influences on the function of the cholinergic system. Scopolamine, however not show any effect on the cAMP level and D_1 receptor in rat brain.
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