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SYNTHESIS OF ACYCLONUCLEOSIDE DERIVATIVES AND ANALOGUES OF 5-FLUOROURACIL[J]. Journal of China Pharmaceutical University, 1986, (3): 161-166.
Citation: SYNTHESIS OF ACYCLONUCLEOSIDE DERIVATIVES AND ANALOGUES OF 5-FLUOROURACIL[J]. Journal of China Pharmaceutical University, 1986, (3): 161-166.
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SYNTHESIS OF ACYCLONUCLEOSIDE DERIVATIVES AND ANALOGUES OF 5-FLUOROURACIL

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  • Twenty five Acyclonucleoside derivatives and analogues of 5-Fluoro-uracil were synthesised in order to search for novel 5-fluorouracil deriva-tive as antineoplastic agents with less side effect and broader margin ofsafety.Condensation of 2,4-bis(
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