SYNTHESIS OF ACYCLONUCLEOSIDE DERIVATIVES AND ANALOGUES OF 5-FLUOROURACIL

SYNTHESIS OF ACYCLONUCLEOSIDE DERIVATIVES AND ANALOGUES OF 5-FLUOROURACIL[J]. Journal of China Pharmaceutical University, 1986, (3): 161-166.

Citation:

SYNTHESIS OF ACYCLONUCLEOSIDE DERIVATIVES AND ANALOGUES OF 5-FLUOROURACIL[J]. Journal of China Pharmaceutical University, 1986, (3): 161-166.

Citation:

SYNTHESIS OF ACYCLONUCLEOSIDE DERIVATIVES AND ANALOGUES OF 5-FLUOROURACIL[J]. Journal of China Pharmaceutical University, 1986, (3): 161-166.

Abstract

Twenty five Acyclonucleoside derivatives and analogues of 5-Fluoro-uracil were synthesised in order to search for novel 5-fluorouracil deriva-tive as antineoplastic agents with less side effect and broader margin ofsafety.Condensation of 2,4-bis(

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