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MATHEMATICS STUDY ON CHARACTERISTICS OF AVERAGE STEADY-STATE FOR DRUGS OBEYING PARALLEL MICHAELIS-MENTEN AND FIRST ORDER KINETICS[J]. Journal of China Pharmaceutical University, 1987, (2): 104-108.
Citation: MATHEMATICS STUDY ON CHARACTERISTICS OF AVERAGE STEADY-STATE FOR DRUGS OBEYING PARALLEL MICHAELIS-MENTEN AND FIRST ORDER KINETICS[J]. Journal of China Pharmaceutical University, 1987, (2): 104-108.

MATHEMATICS STUDY ON CHARACTERISTICS OF AVERAGE STEADY-STATE FOR DRUGS OBEYING PARALLEL MICHAELIS-MENTEN AND FIRST ORDER KINETICS

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  • The Rowland two-compartment model was extended by replacing parallel Michaelis-Menten and first order kinetics from which the equations for the time to reach the steady-state concentration and bioavailability was derived. The relationship between the aver
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