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TOTAL SYNTHESIS OF R,R-(-)-DAURISOLINE[J]. Journal of China Pharmaceutical University, 1988, (3): 161-166.
Citation: TOTAL SYNTHESIS OF R,R-(-)-DAURISOLINE[J]. Journal of China Pharmaceutical University, 1988, (3): 161-166.
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TOTAL SYNTHESIS OF R,R-(-)-DAURISOLINE

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  • Daurisoline(1) was identified as a bisbenzyltetrahydroisoquinoline alkaloid bearing one ether linkage. The key intermediates R-(-)-l-(3'-bromo-4' -benzyloxy)benzyl-1-2-methyl-6-methoxy-7-benzyloxy -1,2,3,4-tetrahydroisoquinoline(3) and R-(-)-l-(4'-hydroxy
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