Studies on Synthesis of Fluoroquinolone Antimicrobial Agent Fleroxacin

Studies on Synthesis of Fluoroquinolone Antimicrobial Agent Fleroxacin[J]. Journal of China Pharmaceutical University, 1995, (6): 321-323.

Citation:

Studies on Synthesis of Fluoroquinolone Antimicrobial Agent Fleroxacin[J]. Journal of China Pharmaceutical University, 1995, (6): 321-323.

Citation:

Studies on Synthesis of Fluoroquinolone Antimicrobial Agent Fleroxacin[J]. Journal of China Pharmaceutical University, 1995, (6): 321-323.

Abstract

An improved synthesis of antibacterial agent fleroxacin,starting from 2,3,4-trifluoronitrobenzene via reduction,condensation-cyclization,fluoroethylation,chelation,piperazination,hydrolysis,etc,was described.The reactions of all steps were carried out und

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