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Ren Yong, Peng Sixun, Hua Weiyi, Zhu Dongya. SynthesisandAntiarhythmicActivityofSome(erythro)-2-Alkyl-3-Phenylpropane-2,3-DiolamineCompounds[J]. Journal of China Pharmaceutical University, 1996, (5).
Citation: Ren Yong, Peng Sixun, Hua Weiyi, Zhu Dongya. SynthesisandAntiarhythmicActivityofSome(erythro)-2-Alkyl-3-Phenylpropane-2,3-DiolamineCompounds[J]. Journal of China Pharmaceutical University, 1996, (5).
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SynthesisandAntiarhythmicActivityofSome(erythro)-2-Alkyl-3-Phenylpropane-2,3-DiolamineCompounds

  • Division of Medicinal Chemistry,China Pharmaceutical Unviersity,Nanjing210009

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  • Guan-fubaseA(GFA),anewantiarhythmicdrugisolatedfromtherootofA-conitumcoreanum,waschosenasaleadcompoundinordertosearchforthenewdrugwithhighpotencyandsimplechemicalstructure.Thedominantcomformationandstructuralpa-rametersofGFAweremodeledandcalculatedwithaSG
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