Synthesis of Dopexamine

Synthesis of Dopexamine[J]. Journal of China Pharmaceutical University, 1999, (5): 328-331.

Citation:

Synthesis of Dopexamine[J]. Journal of China Pharmaceutical University, 1999, (5): 328-331.

Citation:

Synthesis of Dopexamine[J]. Journal of China Pharmaceutical University, 1999, (5): 328-331.

Abstract

An improved process for the preparation 0f dopexamine(1)is described.Compound 1 was synthesized from diamide(2a or 2b) by reduction and demethylation.The diamide(2a or 2b) was prepared from phenylacetic acid or adipic acid. Heating a mixture of an amine a

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