Chemical Modification of Escherichia Coli L-Asparaginase with Polyethylene Glycol

Chemical Modification of Escherichia Coli L-Asparaginase with Polyethylene Glycol[J]. Journal of China Pharmaceutical University, 2000, (3): 72-75.

Citation:

Chemical Modification of Escherichia Coli L-Asparaginase with Polyethylene Glycol[J]. Journal of China Pharmaceutical University, 2000, (3): 72-75.

Citation:

Chemical Modification of Escherichia Coli L-Asparaginase with Polyethylene Glycol[J]. Journal of China Pharmaceutical University, 2000, (3): 72-75.

Abstract

E.coli L asparaginase was modified with SS PEG methoxypolyethylene glycolyl succinimidyl succinate which was prepared in two steps.The modified enzyme activity was maintained 44.52% while the antigenicity was greatly reduced.The modified L aspa

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