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Chemical Modification of Escherichia Coli L-Asparaginase with Polyethylene Glycol[J]. Journal of China Pharmaceutical University, 2000, (3): 72-75.
Citation: Chemical Modification of Escherichia Coli L-Asparaginase with Polyethylene Glycol[J]. Journal of China Pharmaceutical University, 2000, (3): 72-75.
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Chemical Modification of Escherichia Coli L-Asparaginase with Polyethylene Glycol

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  • E.coli L asparaginase was modified with SS PEG [methoxypolyethylene glycolyl succinimidyl succinate] which was prepared in two steps.The modified enzyme activity was maintained 44.52% while the antigenicity was greatly reduced.The modified L aspa
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