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Improved Synthesis of 2-(3-benzoylphenyl) propionitrile[J]. Journal of China Pharmaceutical University, 2001, (3): 27-28.
Citation: Improved Synthesis of 2-(3-benzoylphenyl) propionitrile[J]. Journal of China Pharmaceutical University, 2001, (3): 27-28.

Improved Synthesis of 2-(3-benzoylphenyl) propionitrile

  • 2 (3 benzoylphenyl)propionitrile which is an important intermediate of ketoprofen was synthesized through phase transfer catalytic by four steps, involving Friedel crafts reaction, bromination and cyanation. Pure compound was obtained, and the content o
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