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Synthesis and pharmacological activities of a series of estrogen-rhein hybrid compounds[J]. Journal of China Pharmaceutical University, 2007, 38(1): 25-29.
Citation: Synthesis and pharmacological activities of a series of estrogen-rhein hybrid compounds[J]. Journal of China Pharmaceutical University, 2007, 38(1): 25-29.
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Synthesis and pharmacological activities of a series of estrogen-rhein hybrid compounds

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  • Aim:To design and synthesize the estrogen-rhein hybrid compounds to decrease the simulating effect of estrgen on endometrium and maintaining the effect on bone. Methods:The compounds that link rhein to estrone or estadiol respectively through ethyl-pipera
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