• 中国精品科技期刊
  • 中国高校百佳科技期刊
  • 中国中文核心期刊
  • 中国科学引文数据库核心期刊
Advanced Search
CHEN Liang, TONG Xin-yong, SHI Yuan, TAN Yan. Preparation of fluticasone propionate nasal spray and its spray characteristics[J]. Journal of China Pharmaceutical University, 2010, 41(6): 524-528.
Citation: CHEN Liang, TONG Xin-yong, SHI Yuan, TAN Yan. Preparation of fluticasone propionate nasal spray and its spray characteristics[J]. Journal of China Pharmaceutical University, 2010, 41(6): 524-528.
shu

Preparation of fluticasone propionate nasal spray and its spray characteristics

More Information
    Graphical Abstract
    • Abstract
  • Fluticasone propionate was micronized by the high pressure homogenization method. Box-Behnken design was employed to aid the optimization of the homogenization pressure，cycle frequency and the concentration of drug suspension in the preparation processes.The optimized parameters regarding the micronization process were 50 MPa of the homogenization pressure,6 of the cycle frequency,and 10% of fluticasone propionate in the suspension.The fluticasone propionate nasal spray has a good spraying characteristics with the droplet size distribution and spray pattern in compliance to the specifications of United States Pharmacopeia.
    • FullText(HTML)
    • References (0)
    • Related Articles

  • Related Articles

    [1]SHI Zhengke, CHEN Peipei, ZHANG Yixuan, WEI Jie, DU Yanan, LIU Xiaoquan. Up-regulated miR-452-5p suppressed the expression of RORα and promoted the proliferation and migration of HCC cells[J]. Journal of China Pharmaceutical University, 2022, 53(3): 323-332. DOI: 10.11665/j.issn.1000-5048.20220310
    [2]DUAN Lanlan, DONG Jing, FAN Xiangcheng, ZHU Junyi, ZHANG Yifan, HAN Jichun, SHANG Jing. β-Elemene improves endothelial cells dysfunction, and abnormal proliferation and migration of vascular smooth muscle cells[J]. Journal of China Pharmaceutical University, 2020, 51(3): 333-339. DOI: 10.11665/j.issn.1000-5048.20200311
    [3]XU Manli, WANG Chang, WANG Nan, HE Hongpeng, ZHANG Tongcun, LUO Xuegang. MALAT1 upregulates SMYD3 by competition with miR-124 and promotes proliferation and migration of breast cancer cells[J]. Journal of China Pharmaceutical University, 2019, 50(3): 344-351. DOI: 10.11665/j.issn.1000-5048.20190311
    [4]YIN Xin, SHI Wanyue, PAN Yi, JIN Liang. Mechanism of lncRNA CTD-3252C9.4 on invasion and migration of pancreatic cancer Panc-1 cells in vitro[J]. Journal of China Pharmaceutical University, 2019, 50(2): 230-237. DOI: 10.11665/j.issn.1000-5048.20190215
    [5]WU You, TANG Tingting, ZHU Qinhua, JIN Liang, PAN Yi. Mechanisms of miR-29a in migration and invasion of breast cancer MCF-7 cells in vitro[J]. Journal of China Pharmaceutical University, 2018, 49(3): 348-353. DOI: 10.11665/j.issn.1000-5048.20180314
    [6]XIANG Min, ZHANG Yaqin, WU Pingping, GAO Zhenyu. Effect of block of AGEs-RAGE pathway on the migration of VSMCs[J]. Journal of China Pharmaceutical University, 2016, 47(2): 199-203. DOI: 10.11665/j.issn.1000-5048.20160212
    [7]MA Lidong, WANG Yitong, MENG Xiansheng, BAO Rongrui, WANG Shuai. A cell migration model based on microfluidics and its application for baicalin pharmacodynamics research[J]. Journal of China Pharmaceutical University, 2014, 45(3): 352-357. DOI: 10.11665/j.issn.1000-5048.20140318
    [8]LIN Sensen, WANG Congpin, WAN Shuying, SUN Li, YUAN Shengtao, ZHANG Luyong. Effect of inhibiting CC chemokine receptor 5 on human breast cancer cell adhesion and migration[J]. Journal of China Pharmaceutical University, 2013, 44(4): 362-367. DOI: 10.11665/j.issn.1000-5048.20130415
    [9]WU Mingming, FANG Lei, GOU Shaohua, CHEN Li. 以2-甲基-2-取代苯氧基丙酸为离去基团的铂(Ⅱ)配合物的合成、表征及细胞毒活性[J]. Journal of China Pharmaceutical University, 2013, 44(4): 303-306. DOI: 10.11665/j.issn.1000-5048.20130403
    [10]XU Chang-liang, XI Tao. Anti-migration and anti-angiogenic effects of tanshinone IIA on breast cancer cell MDA-MB-435[J]. Journal of China Pharmaceutical University, 2009, 40(6): 565-570.

Catalog

    Get Citation
    PDF
    XML
    Article views (1787) PDF downloads (2995) Cited by()
    Turn off MathJax
    Article Contents
    Abstract
    Related Articles

    Copyright © Journal of China Pharmaceutical University苏ICP备12050101号-2

    Address：24 Tongjia Lane, Nanjing City, Jiangsu Province （210009）Tel: 025-83271566E-mail: xuebao@cpu.edu.cn

    Supported by: Beijing Renhe Information Technology Co., Ltd.  Baidu Analytics

    Total visits：452288

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return