Experimental therapeutic effect of Shenling capsules on chronic pelvic infla-mmatory disease of animals

To study the experimental therapeutic effect of Shenling capsules on chronic pelvic inflammatory disease,chronic pelvic infection animal models were used to observe the influence of Shenling capsules on the inflammatory and hemorheological change of uterus and oviduct.The anti-inflammatory and antibacterial effect of Shenling capsules was observed in mice model with auricular swelling,model of rat cotton pellet granuloma,and inflammatory model by peritoneal injection.Formation test of serum haemolysin in mice,mice acetic acid writhing and hot plate test were used to observe the effect of Shenling capsules on humoral immunity and their analgesic effect.Shenling capsules obviously inhibited the inflammatory reactions and lesions of model uterus and oviduct,decreased blood viscosity and hematocrit,suppressed mice auricular swelling and cotton pellet granuloma hyperplasia,enhanced livability of infected mice by Escherichia coli and Staphylococcus aureus,enhanced serum haemolysin formation and the function of humoral immunity in mice,reduced the number of writhing and increased pain threshold in mice.It was concluded that Shenling capsules have the action of ameliorating organic lesions and blood circulation,enhancing immune function,and anti-inflammatory,analgesic effect.