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Assistance of artificial intelligence in new drug development
JIANG Zhengyu, YOU Qidong
2024, 55(3): 281-283. DOI: 10.11665/j.issn.1000-5048.2024060302
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Reflections on improving drug success rates with AIDD and CADD
CHEN Baiyu, LYU Lunan, XU Xiaodi, ZHANG Ying, LI Wei, FU Wei
2024, 55(3): 284-294. DOI: 10.11665/j.issn.1000-5048.2024011302
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Research progress of artificial intelligence-based small molecule generation models in drug discovery
TANG qian, CHEN Roufen, SHEN Zheyuan, CHI Xinglong, CHE Jinxin, DONG Xiaowu
2024, 55(3): 295-305. DOI: 10.11665/j.issn.1000-5048.2024031501
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Research on machine learning-based activity prediction models for KRAS inhibitors
DU Ke, RONG Danqi, LU Rui, ZHANG Xiaoya, ZHAO Hongping
2024, 55(3): 306-315. DOI: 10.11665/j.issn.1000-5048.2024031102
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Advances in the application of machine learning in the identification and authentication of synthetic cannabinoids
XU Qing, LYU Min, DENG Hongxiao, HU Chi, XIANG Ping, CHEN Hang
2024, 55(3): 316-325. DOI: 10.11665/j.issn.1000-5048.2023113003
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Optimization of Menin inhibitors based on artificial intelligence-driven molecular factory technology
ZENG Hao, WU Guozhen, ZOU Wuxin, WANG Zhe, SONG Jianfei, SHI Hui, WANG Xiaojian, HOU Tingjun, DENG Yafeng
2024, 55(3): 326-334. DOI: 10.11665/j.issn.1000-5048.2024040904
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Advances in the application of artificial intelligence in nucleic acid drug development
HU Zi’ang, GAO Liming, YU Wenying
2024, 55(3): 335-346. DOI: 10.11665/j.issn.1000-5048.2024033101
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Applications and challenges of artificial intelligence in the development of anticancer peptides
ZHANG Zhixing, DENG Hua, TANG Yun
2024, 55(3): 347-356. DOI: 10.11665/j.issn.1000-5048.2024040201
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Design, synthesis and structure-activity relationship of a series of novel BCR-ABL inhibitors
WANG Yongjian, GUO Ming
2024, 55(3): 357-366. DOI: 10.11665/j.issn.1000-5048.2023042302
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Design, synthesis and antiplatelet aggregation activity of 3-acetyl-7-hydroxycoumarin derivatives
SHANG Feiyang, LIU Chengbo, TAN Hongzhou, HE Bing, HE Liqin
2024, 55(3): 367-374. DOI: 10.11665/j.issn.1000-5048.2023072901
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Design, synthesis and biological activity evaluation of water-soluble borneol phosphate prodrug
ZHANG Lulu, SUN Meiling, QIN Yajuan, LI Tingyou
2024, 55(3): 375-380. DOI: 10.11665/j.issn.1000-5048.2023060703
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Preparation of high-drug-loading cantharidin polymer micelle delivery system and its anti-breast cancer activity
LIU Silu, BAI Yun, WANG Jianhua, ZHANG Keqing, SUN Yanxue, ZHANG Kexin, XU Pengcheng
2024, 55(3): 381-389. DOI: 10.11665/j.issn.1000-5048.2023102501
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Reward effect of flubromazolam and its underlying neural circuit mechanism
HUANG Weiguo, JIANG Weikai, SHAO Yuwei, CHEN Zhigang, TANG Susu, HONG Hao
2024, 55(3): 390-396. DOI: 10.11665/j.issn.1000-5048.2024030401
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Screening of adjuvant for PD-L1 vaccine based on nitrated T cell epitope
ZHOU Hongyou, GAO Xiangdong, YAO Wenbing, TIAN Hong
2024, 55(3): 397-403. DOI: 10.11665/j.issn.1000-5048.2023032801
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Generation and characterization of humanized monoclonal antibody against human IFNAR1
QIU Jiwan, KONG Yong, CHEN Wei, XU Lei, CAO Chunjie, CHEN Tao, WU Yiliang
2024, 55(3): 404-411. DOI: 10.11665/j.issn.1000-5048.2024031401
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Research progress on the function of ectopic olfactory receptors and their value as drug targets
LIU Chang, ZHAO Yongxin, GE Beibei, WEI Bin, GAO Yong
2024, 55(3): 412-419. DOI: 10.11665/j.issn.1000-5048.2023092001
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Research progress in STAT3/Th17 cells and Sjögren syndrome
WANG Jiang, ZHAO Xueyan, FANG Weirong
2024, 55(3): 420-428. DOI: 10.11665/j.issn.1000-5048.2023041805
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