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基于血小板及其膜的仿生递药系统研究进展

徐剑培, 徐群为, 王晓琪, 辛洪亮

徐剑培, 徐群为, 王晓琪, 辛洪亮. 基于血小板及其膜的仿生递药系统研究进展[J]. 中国药科大学学报, 2018, 49(6): 653-659. DOI: 10.11665/j.issn.1000-5048.20180603
引用本文: 徐剑培, 徐群为, 王晓琪, 辛洪亮. 基于血小板及其膜的仿生递药系统研究进展[J]. 中国药科大学学报, 2018, 49(6): 653-659. DOI: 10.11665/j.issn.1000-5048.20180603
XU Jianpei, XU Qunwei, WANG Xiaoqi, XIN Hongliang. Advances in biomimetic drug delivery systems based on platelet and platelet membrane[J]. Journal of China Pharmaceutical University, 2018, 49(6): 653-659. DOI: 10.11665/j.issn.1000-5048.20180603
Citation: XU Jianpei, XU Qunwei, WANG Xiaoqi, XIN Hongliang. Advances in biomimetic drug delivery systems based on platelet and platelet membrane[J]. Journal of China Pharmaceutical University, 2018, 49(6): 653-659. DOI: 10.11665/j.issn.1000-5048.20180603

基于血小板及其膜的仿生递药系统研究进展

基金项目: 国家自然科学基金资助项目(No.31671018)

Advances in biomimetic drug delivery systems based on platelet and platelet membrane

  • 摘要: 血小板是人体血液中重要的固有成分,在机体各类生理反应中发挥重要作用。近年来,基于血小板及其膜的仿生新型药物传递系统备受关注。与传统药物载体相比,血小板及其膜仿生递药系统具有生物相容性好、血液循环时间长和体内靶向性强等优势。本文介绍了基于血小板及其膜仿生递药系统的特点、种类、载药方式及应用,以期促进血小板及其膜仿生载体在药物递送领域的研究与应用。
    Abstract: Platelet is an important component of human blood, which plays a key role in the physiological and pathological processes. Recently, novel drug delivery system based on platelet and platelet membrane bionics attracted much attention. Compared to the traditional drug carriers, platelet and platelet membrane-based biomimetic drug delivery system has great performances in biocompatibility, longer circulation and stronger ability of targeting. This review presented the features, classifications, drug-loading and applications of platelet and platelet membrane-based biomimetic drug delivery systems, promoting their development and application in the future.
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出版历程
  • 刊出日期:  2018-12-24

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