海州常山茎的化学成分研究
Chemical constituents from the stems of Clerodendrum trichotomum Thunb.
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摘要: 采用多种柱色谱方法对大青属Clerodendrum Linn.植物海州常山Clerodendrum trichotomum Thunb.茎的乙醇提取液进行分离纯化，运用波谱学方法鉴定了13个化合物，分别为木栓酮(friedelin， 1 )，白桦脂酸(betulinic acid， 2 )，蒲公英萜醇(taraxerol， 3 )，3-羟基-30-去甲基-20-酮基-28-羽扇豆酸(3-hydroxy-30-nor-20-oxo-28-lupanoic acid，platanic acid， 4 )，金合欢素(acacetin， 5 )，5，7-二羟基3′，4′-二甲氧基黄酮(5，7-dihydroxy 3′，4′-dimethoxyflavone， 6 )，β-谷甾醇(β-sitosterol， 7 )，豆甾醇(stigmasterol， 8 )，胡萝卜苷(daucosterol， 9 )，豆甾醇-3-O-葡萄糖苷(stigmasterol-3-O-glucopyranoside， 10 )，异香草醛(isovanillin， 11 )，邻苯二甲酸二丁酯(dibutyl phthalate， 12 )和丁香醛(syringaldehyde， 13 )。化合物 4 ， 6 ， 11 ~ 13 均为首次从该属植物中分离得到，化合物 4 ， 6，10 ~ 13 为首次从该物种中分离得到。Abstract: Thirteen compounds were isolated and purified from the ethanol extract of Clerodendrum trichotomum Thunb. by various chromatographic methods. Their structures were identified as friedelin( 1 ), betulinic acid( 2 ), taraxerol( 3 ), platanic acid( 4 ), acacetin( 5 ), 5, 7-dihydroxy 3′, 4′-dimethoxyflavone( 6 ), β-sitosterol( 7 ), stigmasterol( 8 ), daucosterol( 9 ), stigmasterol-3-O-glucopyranoside( 10 ), isovanillin( 11 ), dibutyl phthalate( 12 )and syringaldehyde( 13 ). Compounds 4 , 6 , 11- 13 were isolated from genus Clerodendrum Linn. for the first time. Compounds 4 , 6 , 10- 13 were isolated from Clerodendrum trichotomum Thunb. for the first time.
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