Abstract: This paper describes a method of synthesis of a new anti-arrhythmie agent-Au1uton( V Ⅱ.3α-amin-2β-hydroxy-5α-androstan-17-one hvdrochloride ), prepared fromepiandrosterone (an intermediate - derived from tigogenin) by a six-step process. Some reaction conditions have been modified.When Auluton is made from the azido compound(VI) by pd/c catalytic hydrogenation.a by-product (IX mp 199-201℃) has been obtained. Its structure is identified to be 3α-ch1oro-2β-hydorxy-5α-androstan-17-one by chemical and spectral data.