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刘国卿, 蒋莹, 王秋娟, 马俊儒, 谢林, 邹光武, 孙菊芬, 杨启辉. 马辛挥发油的药理研究[J]. 中国药科大学学报, 1982, (2): 88-92.
引用本文: 刘国卿, 蒋莹, 王秋娟, 马俊儒, 谢林, 邹光武, 孙菊芬, 杨启辉. 马辛挥发油的药理研究[J]. 中国药科大学学报, 1982, (2): 88-92.
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Liu Guoqing, Jiang Ying, Wang Qiujuan, Ma Junru, Xie Lin, Zou Guangwu, Sun Jufen, Yang Qihui. THE PHARMACOLOGICAL STUDIES ON ESSENTIAL OIL OF ASARUM FORBESII MAXIM[J]. Journal of China Pharmaceutical University, 1982, (2): 88-92.
Citation: Liu Guoqing, Jiang Ying, Wang Qiujuan, Ma Junru, Xie Lin, Zou Guangwu, Sun Jufen, Yang Qihui. THE PHARMACOLOGICAL STUDIES ON ESSENTIAL OIL OF ASARUM FORBESII MAXIM[J]. Journal of China Pharmaceutical University, 1982, (2): 88-92.
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马辛挥发油的药理研究

THE PHARMACOLOGICAL STUDIES ON ESSENTIAL OIL OF ASARUM FORBESII MAXIM

    摘要
  • 摘要: 马辛(又名细辛)系马兜铃科植物杜衡 Asarum forbesii Maxim 的全草。药理研究表明,马辛挥发油具有明显的中枢抑制作用,能显著减少小鼠自发活动,对戊巴比妥钠或硫喷妥钠有明显协同作用。静脉注射马辛挥发油使兔翻正反射消失约5分钟,能对抗电休克和戊四氮引起的惊厥,能增加小鼠对缺氧的耐受能力,但不能对抗苯两胺的毒性。另外还有降温作用。

     

    Abstract: The pharmacological studies on essential oil of Asarum forbesii Maximd monstratedthat it had a markedly depressant effect on the central nervous system. The essential oil could apparent!y decrease the spontaneous activity in mice (0.15ml/kg i,p.) and potentiate the hypnotic action of pentobarbital or thiopental(O.025 ml/kg i.p.). When injected intravenously (0.05 ml/kg), it caused anaesthetic effect in rabbits.It also antagonized the convulsion induced by e1ectricity or metrazol in mice. It could not antagonize the toxic effect of amphetamine in mice. In addition, essential oil of Asarum forbesii Maxim could also increase the tolerance against anoxiain in mice and reduce body temperature in rats.

     

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