青霉素扩环合成唑啉头孢菌素

青霉素扩环合成唑啉头孢菌素[J]. 中国药科大学学报, 1985, (2): 1-3.

引用本文:

青霉素扩环合成唑啉头孢菌素[J]. 中国药科大学学报, 1985, (2): 1-3.

CONVERSION OF PENICILLIN INTO CEFAZOLIN[J]. Journal of China Pharmaceutical University, 1985, (2): 1-3.

Citation:

CONVERSION OF PENICILLIN INTO CEFAZOLIN[J]. Journal of China Pharmaceutical University, 1985, (2): 1-3.

CONVERSION OF PENICILLIN INTO CEFAZOLIN

摘要: 用3-溴甲基头孢烯酸二苯甲酯-S-氧化物(Ⅰ)合成了唑啉头孢菌素。(Ⅰ)为研制C_(10)~-取代头孢菌素的关键中间体,从苄基青霉素转化而来。

Abstract: CefaZolin was prepared from 3 -bromomethylcephembenzhydry(?)esler S-oxide which is an important intermediat for synthesis of C_(10)-substituted cephalosporins.

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