生理药动学模型及其数值解法

生理药动学模型及其数值解法[J]. 中国药科大学学报, 1987, (4): 273-276.

引用本文:

生理药动学模型及其数值解法[J]. 中国药科大学学报, 1987, (4): 273-276.

PHYSIOLOGICAL MODEL AND NUMERICAL INTEGRATING AGORITHM[J]. Journal of China Pharmaceutical University, 1987, (4): 273-276.

Citation:

PHYSIOLOGICAL MODEL AND NUMERICAL INTEGRATING AGORITHM[J]. Journal of China Pharmaceutical University, 1987, (4): 273-276.

PHYSIOLOGICAL MODEL AND NUMERICAL INTEGRATING AGORITHM

摘要: 本文借助于微分方程组数值解的龙格—库塔方法完成生理药动学模型的数值计算;并对大鼠静注邻乙氧基苯甲酰胺后,根据实验参数值预示了该药物在组织和血浆中浓度—时间曲线。

Abstract: The simultaneous differential equations on physiological pharmacokinetic model were solved by the Range-Kutta method. Concentration-time profiles in tissues or organs of rat following iv 20mg/kg ethoxybenzamine were simulated.

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